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Literature DB >> 2915386

Self-ligating RNA sequences on the antigenome of human hepatitis delta virus.

Abstract

A 179-base fragment of RNA from the 1,679-base antigenome of hepatitis delta virus can not only self-cleave but, when the ends of the resultant fragments are brought into apposition by base pairing to another RNA, also self-ligate. Thus, processing events needed for genome replication in vivo may be strictly RNA mediated.

Entities: Species

Mesh：

Substances：
RNA, Viral

Year: 1989 PMID： 2915386 PMCID： PMC247845 DOI： 10.1128/JVI.63.3.1428-1430.1989

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

12 in total

1. Hydrolytic stability of helical RNA: a selective advantage for the natural 3',5'-bond.

Authors: D A Usher; A H McHale
Journal: Proc Natl Acad Sci U S A Date: 1976-04 Impact factor: 11.205

2. Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites.

Authors: A C Forster; R H Symons
Journal: Cell Date: 1987-04-24 Impact factor: 41.582

3. Molecular cloning of hepatitis delta virus RNA from an infected woodchuck liver: sequence, structure, and applications.

Authors: M Y Kuo; J Goldberg; L Coates; W Mason; J Gerin; J Taylor
Journal: J Virol Date: 1988-06 Impact factor: 5.103

Review 7. Viral hepatitis.

Authors: J Y Lau; G J Alexander; A Alberti
Journal: Gut Date: 1991-09 Impact factor: 23.059

Self-ligating RNA sequences on the antigenome of human hepatitis delta virus.

1. Hydrolytic stability of helical RNA: a selective advantage for the natural 3',5'-bond.

2. Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites.

3. Molecular cloning of hepatitis delta virus RNA from an infected woodchuck liver: sequence, structure, and applications.

4. Characterization of self-cleaving RNA sequences on the genome and antigenome of human hepatitis delta virus.

5. Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site.

Review 6. A replication cycle for viroids and other small infectious RNA's.

7. Nonenzymic joining of oligoadenylates on a polyuridylic acid template.

8. Structure, sequence and expression of the hepatitis delta (delta) viral genome.

9. Antigenomic RNA of human hepatitis delta virus can undergo self-cleavage.

10. Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid.

1. Ribozyme cleavage of a 2,5-phosphodiester linkage: mechanism and a restricted divalent metal-ion requirement.

2. A host-specific function is required for ligation of a wide variety of ribozyme-processed RNAs.

Review 3. RNA replication without RNA-dependent RNA polymerase: surprises from hepatitis delta virus.

4. Regulation of polyadenylation of hepatitis delta virus antigenomic RNA.

5. Ligation of the hairpin ribozyme in cis induced by freezing and dehydration.

6. RNA-mediated ligation of self-cleavage products of a Neurospora mitochondrial plasmid transcript.

Review 7. Viral hepatitis.

8. The antigen of hepatitis delta virus: examination of in vitro RNA-binding specificity.

9. Local helix content and RNA-binding activity of the N-terminal leucine-repeat region of hepatitis delta antigen.

10. A pseudoknot ribozyme structure is active in vivo and required for hepatitis delta virus RNA replication.