Literature DB >> 29153547

Optimization of peptide-based polyagonists for treatment of diabetes and obesity.

Patrick J Knerr1, Brian Finan1, Vasily Gelfanov1, Diego Perez-Tilve2, Matthias H Tschöp3, Richard D DiMarchi4.   

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Year:  2017        PMID: 29153547     DOI: 10.1016/j.bmc.2017.10.047

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


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  5 in total

Review 1.  Structural Basis for Allosteric Modulation of Class B G Protein-Coupled Receptors.

Authors:  Denise Wootten; Laurence J Miller
Journal:  Annu Rev Pharmacol Toxicol       Date:  2019-08-27       Impact factor: 13.820

2.  A phase 1b randomised controlled trial of a glucagon-like peptide-1 and glucagon receptor dual agonist IBI362 (LY3305677) in Chinese patients with type 2 diabetes.

Authors:  Hongwei Jiang; Shuguang Pang; Yawei Zhang; Ting Yu; Meng Liu; Huan Deng; Li Li; Liqi Feng; Baili Song; Han Han-Zhang; Qingyang Ma; Lei Qian; Wenying Yang
Journal:  Nat Commun       Date:  2022-06-24       Impact factor: 17.694

3.  Genetically Encoded Cholesterol-Modified Polypeptides.

Authors:  Davoud Mozhdehi; Kelli M Luginbuhl; Michael Dzuricky; Simone A Costa; Sinan Xiong; Fred C Huang; Mae M Lewis; Stephanie R Zelenetz; Christian D Colby; Ashutosh Chilkoti
Journal:  J Am Chem Soc       Date:  2019-01-04       Impact factor: 15.419

4.  IBI362 (LY3305677), a weekly-dose GLP-1 and glucagon receptor dual agonist, in Chinese adults with overweight or obesity: A randomised, placebo-controlled, multiple ascending dose phase 1b study.

Authors:  Linong Ji; Hongwei Jiang; Pei An; Huan Deng; Meng Liu; Li Li; Liqi Feng; Baili Song; Han Han-Zhang; Qingyang Ma; Lei Qian
Journal:  EClinicalMedicine       Date:  2021-08-13

Review 5.  A compendium of G-protein-coupled receptors and cyclic nucleotide regulation of adipose tissue metabolism and energy expenditure.

Authors:  Ryan P Ceddia; Sheila Collins
Journal:  Clin Sci (Lond)       Date:  2020-03-13       Impact factor: 6.876

  5 in total

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