| Literature DB >> 29150890 |
Syed Mohiyaddin1, Prakash Nanjaiah2, Ahmed O Saad3, Metesh N Acharya4, Tanveer A Khan5, Rhodri H Davies6, Saeed Ashraf1.
Abstract
About 50% of the trauma victims die at the scene mostly because of exsanguinating haemorrhage. Most trials of resuscitation fail in face of the ongoing bleeding. Ongoing research/studies to save these victims by inducing rapid hypothermia using cardiopulmonary bypass as an emergency initial measure along with delayed resuscitation show improved outcomes. A comprehensive review of this research and analysis of studies showed that rapid induction of hypothermia within 5 min of cardiac arrest is associated with better survival and improved neurological outcome. This led us to conclude that suspended animation is a lifesaving modality for the treatment of trauma victims, otherwise hurtling towards certain death. This should be integrated into regular clinical practice. The US Food and Drug Administration has given its approval for clinical trials on such an intervention.Entities:
Keywords: exsanguination; massive haemorrhagic; operative intervention of cardiothoracic trauma; resuscitation
Mesh:
Year: 2017 PMID: 29150890 DOI: 10.1111/ans.14313
Source DB: PubMed Journal: ANZ J Surg ISSN: 1445-1433 Impact factor: 1.872