| Literature DB >> 29149814 |
J L Guerrero Orriach1,2,3, A Ramirez-Fernandez2, J J Escalona-Belmonte2, M Rubio-Navarro2, J Cruz-Manas2.
Abstract
Inodilators are a heterogeneous group of drugs with vasodilatory and inotropic effects. The cardioprotective effect of levosimendan is multifactorial, but now research on levosimendan is focused on the organ-protective properties of this drug in different settings, the regimen that seems to provide the greatest cardiologic and systemic benefits is early administration of levosimendan. We try to answer four questions in this review, which type of patients need this drug? what is the best time to start with it? and the best way that we could give it and finally the reasons for use it. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.Entities:
Keywords: Levosimendan; calcium sensitizers; cardiac surgery; mechanisms; postconditioning; preconditioning.
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Year: 2018 PMID: 29149814 DOI: 10.2174/1570161115666171116150434
Source DB: PubMed Journal: Curr Vasc Pharmacol ISSN: 1570-1611 Impact factor: 2.719