Literature DB >> 29149614

Risky Business: The Circuits that Impact Stress-Induced Decision-Making.

Amy F T Arnsten1, Daeyeol Lee2, Christopher Pittenger3.   

Abstract

How does stress promote risky decision-making? Friedman et al. find that stress disrupts inhibition of striatal circuits by prefrontal cortex, rendering animals insensitive to potential losses. This may help explain how stress contributes to substance abuse and how it can disinhibit automatic behaviors, such as tics in Tourette syndrome.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 29149614     DOI： 10.1016/j.cell.2017.11.004

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  3 in total

1.  Mechanisms underlying prelimbic prefrontal cortex mGlu3/mGlu5-dependent plasticity and reversal learning deficits following acute stress.

Authors:  Max E Joffe; Chiaki I Santiago; Branden J Stansley; James Maksymetz; Rocco G Gogliotti; Julie L Engers; Ferdinando Nicoletti; Craig W Lindsley; P Jeffrey Conn
Journal:  Neuropharmacology       Date:  2018-10-13       Impact factor: 5.250

2.  The role of stress in the pathogenesis and maintenance of obsessive-compulsive disorder.

Authors:  T G Adams; B Kelmendi; C A Brake; P Gruner; C L Badour; C Pittenger
Journal:  Chronic Stress (Thousand Oaks)       Date:  2018-03-04

3.  Disease burden of adverse childhood experiences across 14 states.

Authors:  Geetha M Waehrer; Ted R Miller; Sara C Silverio Marques; Debora L Oh; Nadine Burke Harris
Journal:  PLoS One       Date:  2020-01-28       Impact factor: 3.240
  3 in total

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