Literature DB >> 29149601

Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability.

Kuang Shen, Abigail Choe, David M Sabatini.   

Abstract

Entities:  

Year:  2017        PMID： 29149601      PMCID： PMC5746184          DOI： 10.1016/j.molcel.2017.10.031

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


× No keyword cloud information.
  7 in total

Review 1.  Nutrient regulation of mTORC1 at a glance.

Authors:  Kendall J Condon; David M Sabatini
Journal:  J Cell Sci       Date:  2019-11-13       Impact factor: 5.285

2.  O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine.

Authors:  Kibum Kim; Hee Chan Yoo; Byung Gyu Kim; Sulhee Kim; Yulseung Sung; Ina Yoon; Ya Chun Yu; Seung Joon Park; Jong Hyun Kim; Kyungjae Myung; Kwang Yeon Hwang; Sunghoon Kim; Jung Min Han
Journal:  Nat Commun       Date:  2022-05-25       Impact factor: 17.694

3.  The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction.

Authors:  Shu Yang; Yingbiao Zhang; Chun-Yuan Ting; Lucia Bettedi; Kuikwon Kim; Elena Ghaniam; Mary A Lilly
Journal:  Dev Cell       Date:  2020-09-07       Impact factor: 12.270

Review 4.  mTOR at the nexus of nutrition, growth, ageing and disease.

Authors:  Grace Y Liu; David M Sabatini
Journal:  Nat Rev Mol Cell Biol       Date:  2020-01-14       Impact factor: 94.444

5.  mTOR-Activating Mutations in RRAGD Are Causative for Kidney Tubulopathy and Cardiomyopathy.

Authors:  Karl P Schlingmann; François Jouret; Kuang Shen; Anukrati Nigam; Francisco J Arjona; Claudia Dafinger; Pascal Houillier; Deborah P Jones; Felix Kleinerüschkamp; Jun Oh; Nathalie Godefroid; Mehmet Eltan; Tülay Güran; Stéphane Burtey; Marie-Christine Parotte; Jens König; Alina Braun; Caro Bos; Maria Ibars Serra; Holger Rehmann; Fried J T Zwartkruis; Kirsten Y Renkema; Karin Klingel; Eric Schulze-Bahr; Bernhard Schermer; Carsten Bergmann; Janine Altmüller; Holger Thiele; Bodo B Beck; Karin Dahan; David Sabatini; Max C Liebau; Rosa Vargas-Poussou; Nine V A M Knoers; Martin Konrad; Jeroen H F de Baaij
Journal:  J Am Soc Nephrol       Date:  2021-10-04       Impact factor: 14.978

6.  A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold.

Authors:  Rosalie E Lawrence; Kelvin F Cho; Ronja Rappold; Anna Thrun; Marie Tofaute; Do Jin Kim; Ofer Moldavski; James H Hurley; Roberto Zoncu
Journal:  Nat Cell Biol       Date:  2018-07-30       Impact factor: 28.824

7.  Ait1 regulates TORC1 signaling and localization in budding yeast.

Authors:  Ryan L Wallace; Eric Lu; Xiangxia Luo; Andrew P Capaldi
Journal:  Elife       Date:  2022-09-01       Impact factor: 8.713
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.