Literature DB >> 29148875

Repurposing of Kinase Inhibitors as Broad-Spectrum Antiviral Drugs.

Stanford Schor1,2, Shirit Einav1,2.   

Abstract

The high cost of drug development and the narrow spectrum of coverage typically provided by direct-acting antivirals limit the scalability of this antiviral approach. This review summarizes progress and challenges in the repurposing of approved kinase inhibitors as host-targeted broad-spectrum antiviral therapies.

Keywords:  antiviral drugs; broad-spectrum antivirals; kinase inhibitors; repurposing

Mesh：

Substances：

Year:  2017        PMID： 29148875      PMCID： PMC5804095          DOI： 10.1089/dna.2017.4033

Source DB:  PubMed          Journal:  DNA Cell Biol        ISSN： 1044-5498            Impact factor:   3.311


  69 in total

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