| Literature DB >> 29147035 |
Michael G Lancina1, Hu Yang2,3,4.
Abstract
Existing methods of administering ocular drugs are limited in either their safety or efficiency. Nanomedicine therapies have the potential to address this deficiency by creating vehicles that can control drug biodistribution. Dendrimers are synthetic polymeric nanoparticles with a unique highly organized branching structure. In recent years, promising results using dendrimer vehicles to deliver ocular drugs through different routes of administration have been reported. In this review, we briefly summarize these results with emphasis on the dendrimer modifications used to target different ocular structures.Entities:
Keywords: dendrimer; nanomedicine; ocular drug delivery
Year: 2017 PMID: 29147035 PMCID: PMC5683719 DOI: 10.1139/cjc-2017-0193
Source DB: PubMed Journal: Can J Chem ISSN: 0008-4042 Impact factor: 1.118