Siyi He1, Tom Kosatsky2, Audrey Smargiassi3, Marianne Bilodeau-Bertrand4, Nathalie Auger5. 1. University of Montreal Hospital Research Centre, 900 Saint Denis St, Montreal, Quebec H2X 0A9, Canada; Institut national de santé publique du Québec, 190 Cremazie Blvd E, Montreal, Quebec H2P 1E2, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, 1020 Pine Avenue W, Montreal, Quebec H3A 1A2, Canada. 2. National Collaborating Centre for Environmental Health, British Columbia Centre for Disease Control, 601 West Broadway, Vancouver, British Columbia V5Z 4C2, Canada. 3. Institut national de santé publique du Québec, 190 Cremazie Blvd E, Montreal, Quebec H2P 1E2, Canada; School of Public Health, University of Montreal, 7101 Parc Avenue, Montreal, Quebec H3N 1X9, Canada. 4. University of Montreal Hospital Research Centre, 900 Saint Denis St, Montreal, Quebec H2X 0A9, Canada; Institut national de santé publique du Québec, 190 Cremazie Blvd E, Montreal, Quebec H2P 1E2, Canada. 5. University of Montreal Hospital Research Centre, 900 Saint Denis St, Montreal, Quebec H2X 0A9, Canada; Institut national de santé publique du Québec, 190 Cremazie Blvd E, Montreal, Quebec H2P 1E2, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, 1020 Pine Avenue W, Montreal, Quebec H3A 1A2, Canada; School of Public Health, University of Montreal, 7101 Parc Avenue, Montreal, Quebec H3N 1X9, Canada. Electronic address: nathalie.auger@inspq.qc.ca.
Abstract
INTRODUCTION: Outdoor heat increases the risk of preterm birth and stillbirth, but the association with placental abruption has not been studied. Placental abruption is a medical emergency associated with major morbidity and mortality in pregnancy. We determined the relationship between ambient temperature and risk of placental abruption in warm seasons. MATERIAL AND METHODS: We performed a case-crossover analysis of 17,172 women whose pregnancies were complicated by placental abruption in Quebec, Canada from May to October 1989-2012. The main exposure measure was the maximum temperature reached during the week before abruption. We computed odds ratios (OR) and 95% confidence intervals (CI) for the association of temperature with placental abruption, adjusted for humidity and public holidays. We assessed whether associations were stronger preterm or at term, or varied with maternal age, parity, comorbidity and socioeconomic status. RESULTS: Compared with 15°C, a maximum weekly temperature of 30°C was associated with 1.07 times the odds of abruption (95% CI 0.99-1.16). When the timing of abruption was examined, the associations were significantly stronger at term (OR 1.12, 95% CI 1.02-1.24) than preterm (OR 0.96, 95% CI 0.83-1.10). Relationships were more prominent at term for women who were younger than 35years old, nulliparous or socioeconomically disadvantaged, but did not vary with comorbidity. Associations were stronger within 1 and 5days of abruption. Temperature was not associated with preterm abruption regardless of maternal characteristics. CONCLUSIONS: Elevated temperatures in warm seasons may increase the risk of abruption in women whose pregnancies are near or at term. Pregnant women may be more sensitive to heat and should consider preventive measures such as air conditioning and hydration during hot weather.
INTRODUCTION: Outdoor heat increases the risk of preterm birth and stillbirth, but the association with placental abruption has not been studied. Placental abruption is a medical emergency associated with major morbidity and mortality in pregnancy. We determined the relationship between ambient temperature and risk of placental abruption in warm seasons. MATERIAL AND METHODS: We performed a case-crossover analysis of 17,172 women whose pregnancies were complicated by placental abruption in Quebec, Canada from May to October 1989-2012. The main exposure measure was the maximum temperature reached during the week before abruption. We computed odds ratios (OR) and 95% confidence intervals (CI) for the association of temperature with placental abruption, adjusted for humidity and public holidays. We assessed whether associations were stronger preterm or at term, or varied with maternal age, parity, comorbidity and socioeconomic status. RESULTS: Compared with 15°C, a maximum weekly temperature of 30°C was associated with 1.07 times the odds of abruption (95% CI 0.99-1.16). When the timing of abruption was examined, the associations were significantly stronger at term (OR 1.12, 95% CI 1.02-1.24) than preterm (OR 0.96, 95% CI 0.83-1.10). Relationships were more prominent at term for women who were younger than 35years old, nulliparous or socioeconomically disadvantaged, but did not vary with comorbidity. Associations were stronger within 1 and 5days of abruption. Temperature was not associated with preterm abruption regardless of maternal characteristics. CONCLUSIONS: Elevated temperatures in warm seasons may increase the risk of abruption in women whose pregnancies are near or at term. Pregnant women may be more sensitive to heat and should consider preventive measures such as air conditioning and hydration during hot weather.
Authors: Monika Bączkowska; Katarzyna Kosińska-Kaczyńska; Magdalena Zgliczyńska; Robert Brawura-Biskupski-Samaha; Beata Rebizant; Michał Ciebiera Journal: Int J Environ Res Public Health Date: 2022-04-23 Impact factor: 4.614
Authors: Kathleen E McLean; Rebecca Stranberg; Melissa MacDonald; Gregory R A Richardson; Tom Kosatsky; Sarah B Henderson Journal: Int J Environ Res Public Health Date: 2018-09-19 Impact factor: 3.390
Authors: Yohani Dalugoda; Jyothi Kuppa; Hai Phung; Shannon Rutherford; Dung Phung Journal: Int J Environ Res Public Health Date: 2022-02-04 Impact factor: 3.390
Authors: Emily W Harville; Leslie Beitsch; Christopher K Uejio; Samendra Sherchan; Maureen Y Lichtveld Journal: Int J Disaster Risk Reduct Date: 2021-06-24 Impact factor: 4.842
Authors: Linda C Giudice; Erlidia F Llamas-Clark; Nathaniel DeNicola; Santosh Pandipati; Marya G Zlatnik; Ditas Cristina D Decena; Tracey J Woodruff; Jeanne A Conry Journal: Int J Gynaecol Obstet Date: 2021-10-25 Impact factor: 4.447