| Literature DB >> 29141745 |
Dennis Tappe1, Nina Booken2, Almut Böer-Auer2, Jessica Rauch1, Stefan Schmiedel3, Kristian Reich2.
Abstract
Rickettsia slovaca, a spotted fever group rickettsial pathogen, causes a syndrome consisting of scalp eschar and neck lymphadenopathy following tick bite. We analyzed the histologic skin reaction in the eschar, showing a prominent eosinophilic infiltration, as well as the presence of B lymphocytes and CD4- and CD8-positive T cells. Examination of the serum cytokine responses over time demonstrated an initial proinflammatory cytokine elevation followed by normalization.Entities:
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Year: 2018 PMID: 29141745 PMCID: PMC5928713 DOI: 10.4269/ajtmh.17-0392
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 2.345