| Literature DB >> 29141743 |
Mahamoud Sama Cherif1,2, Shyam Prakash Dumre1, Diénaba Kassé2, Fatoumata Cherif3, Facely Camara2, Alpha Koné2, Mandiou Diakité2, Mohamed Cissé2, Mamadou Pathé Diallo2, Edouard Le Gall4,2, Juntra Karbwang1, Kenji Hirayama1.
Abstract
Elderly people occupy a prominent position in African societies; however, their potential linkage to high case fatality rate (CFR) in Ebola virus disease (EVD) was often overlooked. We describe the predictive factors for EVD lethality in the elderly. A total of 2,004 adults and 309 elderly patients with confirmed EVD were included in the analysis. The median age (interquartile range) was 35 years (23-44) in adults and 65 years (60-70) in the elderly. The proportion of funeral participation was significantly higher in the elderly group than in the adult group. Duration (in days) between the onset of symptoms and admission was significantly longer in elderly. CFR in the elderly people was also significantly higher (80.6%) than in the adult group (66.2%). Funeral participation constituted a risk factor for the transmission of EVD in elderly people.Entities:
Mesh：
Year: 2018 PMID： 29141743 PMCID： PMC5928709 DOI： 10.4269/ajtmh.17-0372
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN： 0002-9637 Impact factor: 2.345