Literature DB >> 2914165

[EEG changes and symptomatic parkinsonism after intracaudate administration of dopamine antibodies].

G N Kryzhanovskiĭ, M A Atadzhanov, S V Magaeva, L A Basharova, L A Vetrilé.   

Abstract

Intracaudate bilateral injection of the dopamine antibodies caused the formation of the generator of pathologically enhanced excitation in caudate nuclei. All the rats exhibited the oligokinesia, rigidity and head tremor were observed in most animals. These abnormalities could be observed during 24 hours. The possible role of dopamine antibodies in parkinsonism pathogenesis is discussed.

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Year:  1989        PMID: 2914165

Source DB:  PubMed          Journal:  Biull Eksp Biol Med        ISSN: 0365-9615


  2 in total

1.  Anti-dopamine antibodies: effects on behavior in an "open field," pain sensitivity, CNS monoamine content, and functional activity of immunocytes in C57Bl/6 mice.

Authors:  N A Trekova; L A Vetrilé; L A Basharova; O I Mikovskaya; T G Khlopushina
Journal:  Neurosci Behav Physiol       Date:  2001 Jan-Feb

2.  Features of the parkinsonian syndrome induced experimentally by a deficit of nigrostriatal dopamine and stimulation of cholinergic neurons of the caudate nuclei.

Authors:  G N Kryzhanovskii; M A Atadzhanov; T A Voronina; L N Nerobkova
Journal:  Neurosci Behav Physiol       Date:  1994 Nov-Dec
  2 in total

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