Literature DB >> 29140501

Understanding the Association Between Negative Symptoms and Performance on Effort-Based Decision-Making Tasks: The Importance of Defeatist Performance Beliefs.

L Felice Reddy1,2, William P Horan1,2, Deanna M Barch3, Robert W Buchanan4, James M Gold4, Stephen R Marder1,2, Jonathan K Wynn1,2, Jared Young5,6, Michael F Green1,2.   

Abstract

Effort-based decision-making paradigms are increasingly utilized to gain insight into the nature of motivation deficits. Research has shown associations between effort-based decision making and experiential negative symptoms; however, the associations are not consistent. The current study had two primary goals. First, we aimed to replicate previous findings of a deficit in effort-based decision making among individuals with schizophrenia on a test of cognitive effort. Second, in a large sample combined from the current and a previous study, we sought to examine the association between negative symptoms and effort by including the related construct of defeatist beliefs. The results replicated previous findings of impaired cognitive effort-based decision making in schizophrenia. Defeatist beliefs significantly moderated the association between negative symptoms and effort-based decision making such that there was a strong association between high negative symptoms and deficits in effort-based decision making, but only among participants with high levels of defeatist beliefs. Thus, our findings suggest the relationship between negative symptoms and effort performance may be understood by taking into account the role of defeatist beliefs, and finding that might explain discrepancies in previous studies.

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Year:  2018        PMID: 29140501      PMCID: PMC6192468          DOI: 10.1093/schbul/sbx156

Source DB:  PubMed          Journal:  Schizophr Bull        ISSN: 0586-7614            Impact factor:   9.306


  45 in total

1.  The NIMH-MATRICS consensus statement on negative symptoms.

Authors:  Brian Kirkpatrick; Wayne S Fenton; William T Carpenter; Stephen R Marder
Journal:  Schizophr Bull       Date:  2006-02-15       Impact factor: 9.306

2.  The Positive and Negative Syndrome Scale (PANSS): rationale and standardisation.

Authors:  S R Kay; L A Opler; J P Lindenmayer
Journal:  Br J Psychiatry Suppl       Date:  1989-11

3.  The current conceptualization of negative symptoms in schizophrenia.

Authors:  Stephen R Marder; Silvana Galderisi
Journal:  World Psychiatry       Date:  2017-02       Impact factor: 49.548

4.  Prefrontal cortex, cognitive control, and the registration of decision costs.

Authors:  Joseph T McGuire; Matthew M Botvinick
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-12       Impact factor: 11.205

5.  From perception to functional outcome in schizophrenia: modeling the role of ability and motivation.

Authors:  Michael F Green; Gerhard Hellemann; William P Horan; Junghee Lee; Jonathan K Wynn
Journal:  Arch Gen Psychiatry       Date:  2012-12

6.  Randomized trial to evaluate the efficacy of cognitive therapy for low-functioning patients with schizophrenia.

Authors:  Paul M Grant; Gloria A Huh; Dimitri Perivoliotis; Neal M Stolar; Aaron T Beck
Journal:  Arch Gen Psychiatry       Date:  2011-10-03

7.  Further support for the role of dysfunctional attitudes in models of real-world functioning in schizophrenia.

Authors:  William P Horan; Yuri Rassovsky; Robert S Kern; Junghee Lee; Jonathan K Wynn; Michael F Green
Journal:  J Psychiatr Res       Date:  2009-12-14       Impact factor: 4.791

8.  Apathy but not diminished expression in schizophrenia is associated with discounting of monetary rewards by physical effort.

Authors:  Matthias N Hartmann; Oliver M Hager; Anna V Reimann; Justin R Chumbley; Matthias Kirschner; Erich Seifritz; Philippe N Tobler; Stefan Kaiser
Journal:  Schizophr Bull       Date:  2014-07-22       Impact factor: 9.306

9.  Negative symptoms of schizophrenia are associated with abnormal effort-cost computations.

Authors:  James M Gold; Gregory P Strauss; James A Waltz; Benjamin M Robinson; Jamie K Brown; Michael J Frank
Journal:  Biol Psychiatry       Date:  2013-02-07       Impact factor: 13.382

10.  Randomized clinical trial of cognitive behavioral social skills training for schizophrenia: improvement in functioning and experiential negative symptoms.

Authors:  Eric Granholm; Jason Holden; Peter C Link; John R McQuaid
Journal:  J Consult Clin Psychol       Date:  2014-06-09
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  9 in total

1.  Clarifying the overlap between motivation and negative symptom measures in schizophrenia research: A meta-analysis.

Authors:  Lauren Luther; Melanie W Fischer; Ruth L Firmin; Michelle P Salyers
Journal:  Schizophr Res       Date:  2018-12-19       Impact factor: 4.939

Review 2.  Cognition and Reward Circuits in Schizophrenia: Synergistic, Not Separate.

Authors:  A J Robison; Katharine N Thakkar; Vaibhav A Diwadkar
Journal:  Biol Psychiatry       Date:  2019-10-03       Impact factor: 13.382

Review 3.  A review of risky decision-making in psychosis-spectrum disorders.

Authors:  John R Purcell; Emma N Herms; Jaime Morales; William P Hetrick; Krista M Wisner; Joshua W Brown
Journal:  Clin Psychol Rev       Date:  2021-12-20

4.  Objective Versus Subjective Effort in Schizophrenia.

Authors:  Isabel Kreis; Steffen Moritz; Gerit Pfuhl
Journal:  Front Psychol       Date:  2020-07-09

5.  Reduced Neural Sensitivity to Social vs Nonsocial Reward in Schizophrenia.

Authors:  Junghee Lee; Amy M Jimenez; Eric A Reavis; William P Horan; Jonathan K Wynn; Michael F Green
Journal:  Schizophr Bull       Date:  2019-04-25       Impact factor: 9.306

6.  Reward processing in certain versus uncertain contexts in schizophrenia: An event-related potential (ERP) study.

Authors:  Peter E Clayson; Jonathan K Wynn; Zachary P Infantolino; Greg Hajcak; Michael F Green; William P Horan
Journal:  J Abnorm Psychol       Date:  2019-11

Review 7.  Psychological Dimensions Relevant to Motivation and Pleasure in Schizophrenia.

Authors:  Samantha V Abram; Lauren P Weittenhiller; Claire E Bertrand; John R McQuaid; Daniel H Mathalon; Judith M Ford; Susanna L Fryer
Journal:  Front Behav Neurosci       Date:  2022-03-23       Impact factor: 3.558

Review 8.  MDMA for the Treatment of Negative Symptoms in Schizophrenia.

Authors:  Mitchell D Arnovitz; Andrew J Spitzberg; Ashkhan J Davani; Nehal P Vadhan; Julie Holland; John M Kane; Timothy I Michaels
Journal:  J Clin Med       Date:  2022-06-07       Impact factor: 4.964

9.  The effect of salience of rewards on effort-based decision making in psychotic disorders.

Authors:  Katharina E Renz; Tania M Lincoln
Journal:  BMC Psychiatry       Date:  2022-10-13       Impact factor: 4.144

  9 in total

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