Literature DB >> 29138777

Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes.

Kyle L Fort1, Michiel van de Waterbeemd, Dmitriy Boll, Maria Reinhardt-Szyba, Mikhail E Belov, Eita Sasaki, Reinhard Zschoche, Donald Hilvert, Alexander A Makarov, Albert J R Heck.   

Abstract

Native mass spectrometry can provide insight into the structure of macromolecular biological systems. As analytes under investigation get larger and more complex, instrument capabilities need to be advanced. Herein, modifications to an Orbitrap Q Exactive Plus mass spectrometer that increase signal intensity, mass resolution, and maximum m/z measurable are described.

Year:  2017        PMID： 29138777     DOI： 10.1039/c7an01629h

Source DB:  PubMed          Journal:  Analyst        ISSN： 0003-2654            Impact factor:   4.616


  34 in total

1.  First-Principles Collision Cross Section Measurements of Large Proteins and Protein Complexes.

Authors:  Jacob W McCabe; Christopher S Mallis; Klaudia I Kocurek; Michael L Poltash; Mehdi Shirzadeh; Michael J Hebert; Liqi Fan; Thomas E Walker; Xueyun Zheng; Ting Jiang; Shiyu Dong; Cheng-Wei Lin; Arthur Laganowsky; David H Russell
Journal:  Anal Chem       Date:  2020-07-28       Impact factor: 6.986

2.  Recent Developments in Gas-Phase Ion/Ion Reactions for Analytical Mass Spectrometry.

Authors:  David J Foreman; Scott A McLuckey
Journal:  Anal Chem       Date:  2019-11-26       Impact factor: 6.986

3.  Simple and Minimally Invasive SID Devices for Native Mass Spectrometry.

Authors:  Dalton T Snyder; Erin M Panczyk; Arpad Somogyi; Desmond A Kaplan; Vicki Wysocki
Journal:  Anal Chem       Date:  2020-08-07       Impact factor: 6.986

4.  Surface-Induced Dissociation: An Effective Method for Characterization of Protein Quaternary Structure.

Authors:  Alyssa Q Stiving; Zachary L VanAernum; Florian Busch; Sophie R Harvey; Samantha H Sarni; Vicki H Wysocki
Journal:  Anal Chem       Date:  2018-12-18       Impact factor: 6.986

5.  Design and Performance of a Second-Generation Surface-Induced Dissociation Cell for Fourier Transform Ion Cyclotron Resonance Mass Spectrometry of Native Protein Complexes.

Authors:  Dalton T Snyder; Erin Panczyk; Alyssa Q Stiving; Joshua D Gilbert; Arpad Somogyi; Desmond Kaplan; Vicki Wysocki
Journal:  Anal Chem       Date:  2019-10-22       Impact factor: 6.986

6.  The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function.

Authors:  Ruth A Singer; Luis Arnes; Yi Cui; Jiguang Wang; Yuqian Gao; Michelle A Guney; Kristin E Burnum-Johnson; Raul Rabadan; Charles Ansong; Galya Orr; Lori Sussel
Journal:  Cell Metab       Date:  2019-10-10       Impact factor: 27.287

Review 7.  Evolution of Structural Biology through the Lens of Mass Spectrometry.

Authors:  Upneet Kaur; Danté T Johnson; Emily E Chea; Daniel J Deredge; Jessica A Espino; Lisa M Jones
Journal:  Anal Chem       Date:  2018-12-06       Impact factor: 6.986

8.  Uniting Native Capillary Electrophoresis and Multistage Ultraviolet Photodissociation Mass Spectrometry for Online Separation and Characterization of Escherichia coli Ribosomal Proteins and Protein Complexes.

Authors:  M Rachel Mehaffey; Qiangwei Xia; Jennifer S Brodbelt
Journal:  Anal Chem       Date:  2020-11-06       Impact factor: 6.986

9.  Surface-Induced Dissociation of Noncovalent Protein Complexes in an Extended Mass Range Orbitrap Mass Spectrometer.

Authors:  Zachary L VanAernum; Joshua D Gilbert; Mikhail E Belov; Alexander A Makarov; Stevan R Horning; Vicki H Wysocki
Journal:  Anal Chem       Date:  2019-02-12       Impact factor: 6.986

10.  Native vs Denatured: An in Depth Investigation of Charge State and Isotope Distributions.

Authors:  Jared O Kafader; Rafael D Melani; Luis F Schachner; Ashley N Ives; Steven M Patrie; Neil L Kelleher; Philip D Compton
Journal:  J Am Soc Mass Spectrom       Date:  2020-02-04       Impact factor: 3.109
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