Literature DB >> 29136500

Does CSF1R Blockade Turn into Friendly Fire?

Tim F Greten1.   

Abstract

In this issue of Cancer Cell, Kumar et al. describe how CSF1R blockade induces not only an expected deprivation of tumor-associated macrophages, but also an accumulation of tumor-infiltrating polymorphonuclear mononuclear cells caused by Cxcl-1 released from cancer-associated fibroblasts. Published by Elsevier Inc.

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Year:  2017        PMID: 29136500      PMCID: PMC6309824          DOI: 10.1016/j.ccell.2017.10.012

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  8 in total

Review 1.  T cell exclusion, immune privilege, and the tumor microenvironment.

Authors:  Johanna A Joyce; Douglas T Fearon
Journal:  Science       Date:  2015-04-03       Impact factor: 47.728

2.  CD49d is a new marker for distinct myeloid-derived suppressor cell subpopulations in mice.

Authors:  Lydia A Haile; Jaba Gamrekelashvili; Michael P Manns; Firouzeh Korangy; Tim F Greten
Journal:  J Immunol       Date:  2010-06-04       Impact factor: 5.422

3.  Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors.

Authors:  Vinit Kumar; Laxminarasimha Donthireddy; Douglas Marvel; Thomas Condamine; Fang Wang; Sergio Lavilla-Alonso; Ayumi Hashimoto; Prashanthi Vonteddu; Reeti Behera; Marlee A Goins; Charles Mulligan; Brian Nam; Neil Hockstein; Fred Denstman; Shanti Shakamuri; David W Speicher; Ashani T Weeraratna; Timothy Chao; Robert H Vonderheide; Lucia R Languino; Peter Ordentlich; Qin Liu; Xiaowei Xu; Albert Lo; Ellen Puré; Chunsheng Zhang; Andrey Loboda; Manuel A Sepulveda; Linda A Snyder; Dmitry I Gabrilovich
Journal:  Cancer Cell       Date:  2017-11-13       Impact factor: 31.743

4.  Entinostat Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma.

Authors:  Ashley Orillion; Ayumi Hashimoto; Nur Damayanti; Li Shen; Remi Adelaiye-Ogala; Sreevani Arisa; Sreenivasulu Chintala; Peter Ordentlich; Chingai Kao; Bennett Elzey; Dmitry Gabrilovich; Roberto Pili
Journal:  Clin Cancer Res       Date:  2017-07-11       Impact factor: 12.531

5.  Histone deacetylase inhibitors deplete myeloid-derived suppressor cells induced by 4T1 mammary tumors in vivo and in vitro.

Authors:  Hai-Fang Wang; Fen Ning; Zong-Cai Liu; Long Wu; Zi-Qian Li; Yi-Fei Qi; Ge Zhang; Hong-Sheng Wang; Shao-Hui Cai; Jun Du
Journal:  Cancer Immunol Immunother       Date:  2016-12-03       Impact factor: 6.968

Review 6.  Myeloid-derived suppressor cell heterogeneity in human cancers.

Authors:  Samantha Solito; Ilaria Marigo; Laura Pinton; Vera Damuzzo; Susanna Mandruzzato; Vincenzo Bronte
Journal:  Ann N Y Acad Sci       Date:  2014-06       Impact factor: 5.691

7.  Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells.

Authors:  KiBem Kim; Andrew D Skora; Zhaobo Li; Qiang Liu; Ada J Tam; Richard L Blosser; Luis A Diaz; Nickolas Papadopoulos; Kenneth W Kinzler; Bert Vogelstein; Shibin Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2014-07-28       Impact factor: 11.205

Review 8.  Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy.

Authors:  Michael A Cannarile; Martin Weisser; Wolfgang Jacob; Anna-Maria Jegg; Carola H Ries; Dominik Rüttinger
Journal:  J Immunother Cancer       Date:  2017-07-18       Impact factor: 13.751

  8 in total

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