Literature DB >> 29134366

Genetic characteristics of 19 STRs in Chinese Uzbek ethnic and its phylogenetic relationships with other 24 populations.

Xiaoye Jin1,2,3, Wei Cui1,2,3, Yuanyuan Wei1,2, Yuling Mu1,2,3, Qian Dong1,2,3, Chong Chen1,2,3, Yuxin Guo1,2,3, Tingting Kong1,2, Bofeng Zhu1,2,4, Jiangang Chen5,6.   

Abstract

Allelic frequencies and genetic polymorphisms of 19 short tandem repeats loci were investigated so as to provide more genetic data for forensic applications in Chinese Uzbek group; besides, we evaluated phylogenetic relationships of Uzbek group with other populations. All loci were observed to conform to Hardy-Weinberg equilibrium after Bonferroni's correction. Two hundred and nine alleles were identified in 212 unrelated healthy Uzbek individuals and their allelic frequencies ranged from 0.0024 to 0.5259. The cumulative discrimination power and cumulative probability of exclusion were 0.999999999999999999999996501 and 0.999999998759, respectively. The results of population differentiation comparison, principal component analysis, and phylogenetic tree revealed that Uzbek group had close relationships with Uyghur and Kazakh groups.

Keywords:  Genetic characteristics; Phylogenetic relationships; STR; Uzbek ethnic group

Mesh:

Year:  2017        PMID: 29134366     DOI: 10.1007/s00414-017-1717-0

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


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  5 in total
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  2 in total

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