Literature DB >> 29132255

Selected Radiation Safety Aspects Including Transportation and Lodging After Outpatient 131I Therapy for Differentiated Thyroid Cancer.

Cristiane J Gomes-Lima1,2, Di Wu1,3, Pejman H Kharazi3, Gauri J Khojekar4, Matthew D Ringel5, Richard J Vetter6, Gary Bloom7, Kenneth D Burman2, Leonard Wartofsky2, Douglas Van Nostrand1,3.   

Abstract

BACKGROUND: Whether radioactive iodine (131I) treatments for differentiated thyroid cancer should be performed as an outpatient or inpatient remains controversial. The objective of this study was to survey selected aspects of radiation safety of patients treated with 131I for differentiated thyroid cancer as an outpatient.
METHODS: An e-mail invitation was sent to over 15,000 members of ThyCa: Thyroid Cancer Survivors' Association, Inc. to complete a web-based survey on selected aspects of radiation safety regarding their last outpatient 131I treatment.
RESULTS: A total of 1549 patients completed the survey. Forty-five percent (699/1541) of the respondents reported no discussion on the choice of an inpatient or outpatient treatment. Moreover, 5% (79/1541) of the respondents reported that their insurance company made the decision. Survey respondents recalled receiving oral and written radiation safety instructions 97% (1459/1504) and 93% (1351/1447) of the time, respectively. Nuclear medicine physicians delivered oral and written instructions to 54% (807/1504) and 41% (602/1462) of the respondents, respectively. Eighty-eight percent (1208/1370) of the respondents were discharged within 1 hour after receiving their 131I treatment, and 97% (1334/1373) traveled in their own car after being released from the treating facility. Immediately post-therapy, 94% (1398/1488) of the respondents stayed at their own home or a relative's home, while 5% (76/1488) resided in a public lodging. The specific recommendations received by patients about radiation precautions varied widely among the respondents. Ninety-nine percent (1451/1467) of the respondents believed they were compliant with the instructions.
CONCLUSION: This is the largest, patient-based survey published regarding selected radiation safety aspects of outpatient 131I treatment. This survey suggests several concerns about radiation safety, such as the decision process regarding inpatient versus outpatient treatment, instructions about radiation safety, transportation, and lodging after radioiodine therapy. These concerns warrant further discussion, guidelines, and/or policies.

Entities:  

Keywords:  131I; differentiated thyroid cancer; outpatient; radiation safety; radioiodine

Mesh:

Substances:

Year:  2017        PMID: 29132255      PMCID: PMC7003059          DOI: 10.1089/thy.2017.0124

Source DB:  PubMed          Journal:  Thyroid        ISSN: 1050-7256            Impact factor:   6.568


  12 in total

1.  Current safety practices relating to I-131 administration for diseases of the thyroid: a survey of physicians and allied practitioners.

Authors:  Carol Greenlee; Lynn A Burmeister; Robert S Butler; Charlotte H Edinboro; Shannon McIntyre Morrison; Mira Milas
Journal:  Thyroid       Date:  2011-02       Impact factor: 6.568

2.  Comments regarding Practice Recommendations of the American Thyroid Association for radiation safety in the treatment of thyroid disease with radioiodine.

Authors:  James V Hennessey; J Anthony Parker; Rosemary Kennedy; Jeffrey R Garber
Journal:  Thyroid       Date:  2012-02-03       Impact factor: 6.568

3.  The SNMMI practice guideline for therapy of thyroid disease with 131I 3.0.

Authors:  Edward B Silberstein; Abass Alavi; Helena R Balon; Susan E M Clarke; Chaitanya Divgi; Michael J Gelfand; Stanley J Goldsmith; Hossein Jadvar; Carol S Marcus; William H Martin; J Anthony Parker; Henry D Royal; Salil D Sarkar; Michael Stabin; Alan D Waxman
Journal:  J Nucl Med       Date:  2012-07-11       Impact factor: 10.057

4.  New scrutiny of outpatient therapy with I-131.

Authors:  Jay A Harolds
Journal:  Clin Nucl Med       Date:  2011-03       Impact factor: 7.794

5.  Survey of patient release information on radiation and security checkpoints.

Authors:  Luba Katz; Armin Ansari
Journal:  J Nucl Med       Date:  2007-12       Impact factor: 10.057

6.  A closer look at the latest NRC patient release guidance.

Authors:  Jeffry A Siegel; Edward B Silberstein
Journal:  J Nucl Med       Date:  2008-07       Impact factor: 10.057

7.  Radiation exposure from outpatient radioactive iodine (131I) therapy for thyroid carcinoma.

Authors:  P W Grigsby; B A Siegel; S Baker; J O Eichling
Journal:  JAMA       Date:  2000-05-03       Impact factor: 56.272

8.  Radiation safety in the treatment of patients with thyroid diseases by radioiodine 131I : practice recommendations of the American Thyroid Association.

Authors:  James C Sisson; John Freitas; Iain Ross McDougall; Lawrence T Dauer; James R Hurley; James D Brierley; Charlotte H Edinboro; David Rosenthal; Michael J Thomas; Jason A Wexler; Ernest Asamoah; Anca M Avram; Mira Milas; Carol Greenlee
Journal:  Thyroid       Date:  2011-03-18       Impact factor: 6.568

9.  Outpatient radioiodine therapy for thyroid cancer: a safe nuclear medicine procedure.

Authors:  José Willegaignon; Marcelo Sapienza; Carla Ono; Tomoco Watanabe; Maria Inês Guimarães; Ricardo Gutterres; Maria Helena Marechal; Carlos Buchpiguel
Journal:  Clin Nucl Med       Date:  2011-06       Impact factor: 7.794

Review 10.  Treatment of thyroid carcinoma: emphasis on high-dose 131I outpatient therapy.

Authors:  K Laxman Parthasarathy; Elpida S Crawford
Journal:  J Nucl Med Technol       Date:  2002-12
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  2 in total

1.  Do Current Radiation Safety Guidelines allow the Safe Release of a Thyroid Cancer Patient after High-dose Radioiodine Therapy? An Indian Perspective.

Authors:  Subhash Chand Kheruka; Nilesh Shankar; Manish Ora; Sanjay Gambhir
Journal:  Indian J Nucl Med       Date:  2021-06-21

2.  Upregulation of OIP5-AS1 Predicts Poor Prognosis and Contributes to Thyroid Cancer Cell Proliferation and Migration.

Authors:  Qiuli Li; Weichao Chen; Rongzhen Luo; Zhiyi Zhang; Ming Song; Wenkuan Chen; Zhongyuan Yang; Yuanzhong Yang; Zhuming Guo; Ankui Yang
Journal:  Mol Ther Nucleic Acids       Date:  2020-01-11       Impact factor: 8.886

  2 in total

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