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Literature DB >> 29131713

Vaccines We Need But Don't Have.

Abstract

Vaccinations have had tremendous success in the 20th century. However, in the 21st century, we are facing complex immunological issues in relation to controlling underlying infectious diseases. Therefore, new technologies are needed to develop vaccines against infectious diseases like respiratory syncytial virus, human immunodeficiency virus, and cytomegalovirus. In addition, recent emerging infections have taught us that we must prepare preventative measures in advance using our scientific abilities.

Entities: Disease Species

Keywords: live vaccine development; vaccine improvement; vaccine replacement

Mesh：

Substances：
Vaccines

Year: 2017 PMID： 29131713 DOI： 10.1089/vim.2017.0126

Source DB: PubMed Journal: Viral Immunol ISSN： 0882-8245 Impact factor: 2.257

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Cited

5 in total

1. Targeted Amino Acid Substitution Overcomes Scale-Up Challenges with the Human C5a-Derived Decapeptide Immunostimulant EP67.

Authors: Abdulraman M Alshammari; D David Smith; Jake Parriott; Jason P Stewart; Stephen M Curran; Russell J McCulloh; Peter A Barry; Smita S Iyer; Nicholas Palermo; Joy A Phillips; Yuxiang Dong; Donald R Ronning; Jonathan L Vennerstrom; Sam D Sanderson; Joseph A Vetro
Journal: ACS Infect Dis Date: 2020-04-13 Impact factor: 5.084

2. 3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates.

Authors: Sudhir Pai Kasturi; Mohammed Ata Ur Rasheed; Colin Havenar-Daughton; Mathew Pham; Traci Legere; Zarpheen Jinnah Sher; Yevgeny Kovalenkov; Sanjeev Gumber; Jessica Y Huang; Raphael Gottardo; William Fulp; Alicia Sato; Sheetal Sawant; Sherry Stanfield-Oakley; Nicole Yates; Celia LaBranche; S Munir Alam; Georgia Tomaras; Guido Ferrari; David Montefiori; Jens Wrammert; Francois Villinger; Mark Tomai; John Vasilakos; Christopher B Fox; Steven G Reed; Barton F Haynes; Shane Crotty; Rafi Ahmed; Bali Pulendran
Journal: Sci Immunol Date: 2020-06-19

Vaccines We Need But Don't Have.

1. Targeted Amino Acid Substitution Overcomes Scale-Up Challenges with the Human C5a-Derived Decapeptide Immunostimulant EP67.

2. 3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates.

Review 3. So much at stake: Ethical tradeoffs in accelerating SARSCoV-2 vaccine development.

Review 4. Recent Advances in the Use of Plant Virus-Like Particles as Vaccines.

Review 5. Myeloid-derived suppressor cells and vaccination against pathogens.