BACKGROUND: Extremely preterm birth is associated with a high risk of extrauterine growth retardation, which has been linked with adverse developmental outcomes. OBJECTIVE: We investigated whether nutritional management during the first 7 days of life affects growth patterns until the corrected age of 2 years in extremely preterm infants. STUDY DESIGN: A retrospective study of 78 extremely preterm (<28 weeks' gestation) neonates was conducted. Data regarding parenteral and enteral intake of energy, protein, lipids, and carbohydrates during the first 7 days of life were collected from patient records. The outcome measures included weight, height, and head circumference with Z scores at term-equivalent age and the corrected ages of 1 and 2 years. Analyses were performed with hierarchical-linear mixed models. RESULTS: Nutritional intake during the first week of life did not reach the current recommendations. The total energy intake during the first 7 days of life was statistically significantly associated with weight, length, and head circumference until the corrected age of 2 years after adjusting for potential confounding factors. Individual macronutrient intake displayed no association with growth patterns. CONCLUSIONS: Energy intake during the first 7 days of life is associated with growth until the corrected age of 2 years. These results provide support for the aggressive early nutritional management of extremely preterm infants.
BACKGROUND: Extremely preterm birth is associated with a high risk of extrauterine growth retardation, which has been linked with adverse developmental outcomes. OBJECTIVE: We investigated whether nutritional management during the first 7 days of life affects growth patterns until the corrected age of 2 years in extremely preterm infants. STUDY DESIGN: A retrospective study of 78 extremely preterm (<28 weeks' gestation) neonates was conducted. Data regarding parenteral and enteral intake of energy, protein, lipids, and carbohydrates during the first 7 days of life were collected from patient records. The outcome measures included weight, height, and head circumference with Z scores at term-equivalent age and the corrected ages of 1 and 2 years. Analyses were performed with hierarchical-linear mixed models. RESULTS: Nutritional intake during the first week of life did not reach the current recommendations. The total energy intake during the first 7 days of life was statistically significantly associated with weight, length, and head circumference until the corrected age of 2 years after adjusting for potential confounding factors. Individual macronutrient intake displayed no association with growth patterns. CONCLUSIONS: Energy intake during the first 7 days of life is associated with growth until the corrected age of 2 years. These results provide support for the aggressive early nutritional management of extremely preterm infants.
Authors: Mariana M Oliveira; Davi C Aragon; Vanessa S Bomfim; Tânia M B Trevilato; Larissa G Alves; Anália R Heck; Francisco E Martinez; José S Camelo Journal: PLoS One Date: 2019-02-20 Impact factor: 3.240
Authors: Alida Kindt; Yvonne Kraus; David Rasp; Kai M Foerster; Narges Ahmidi; Andreas W Flemmer; Susanne Herber-Jonat; Florian Heinen; Heike Weigand; Thomas Hankemeier; Berthold Koletzko; Jan Krumsiek; Juergen Babl; Anne Hilgendorff Journal: Nutrients Date: 2022-09-21 Impact factor: 6.706
Authors: Erin E Morris; Neely C Miller; Nicholas A Marka; Jennifer L Super; Emily M Nagel; Juan David Gonzalez; Ellen W Demerath; Sara E Ramel Journal: Nutrients Date: 2022-09-20 Impact factor: 6.706