Literature DB >> 29129650

Forecasting the future burden of opioids for osteoarthritis.

I N Ackerman1, E Zomer2, J F-M Gilmartin-Thomas3, D Liew2.   

Abstract

OBJECTIVE: To quantify the current national burden of opioids for osteoarthritis (OA) pain in Australia in terms of number of dispensed opioid prescriptions and associated costs, and to forecast the likely burden to the year 2030/31.
DESIGN: Epidemiological modelling.
METHODS: Published data were obtained on rates of opioid prescribing for people with OA and national OA prevalence projections. Trends in opioid dispensing from 2006 to 2016, and average costs for common opioid subtypes were obtained from the Pharmaceutical Benefits Scheme and Medicare Australia Statistics. Using these inputs, a model was developed to estimate the likely number of dispensed opioid prescriptions and costs to the public healthcare system by 2030/31.
RESULTS: In 2015/16, an estimated 1.1 million opioid prescriptions were dispensed in Australia for 403,954 people with OA (of a total 2.2 million Australians with OA). Based on recent dispensing trends and OA prevalence projections, the number of dispensed opioid prescriptions is expected to nearly triple to 3,032,332 by 2030/31, for an estimated 562,610 people with OA. The estimated cost to the Australian healthcare system was $AUD25.2 million in 2015/16, rising to $AUD72.4 million by 2030/31.
CONCLUSION: OA-related opioid dispensing and associated costs are set to increase substantially in Australia from 2015/16 to 2030/31. Use of opioids for OA pain is concerning given joint disease chronicity and the risk of adverse events, particularly among older people. These projections represent a conservative estimate of the full financial burden given additional costs associated with opioid-related harms and out-of-pocket costs borne by patients.
Copyright © 2017 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Healthcare costs; Opioid analgesics; Osteoarthritis

Mesh:

Substances:

Year:  2017        PMID: 29129650     DOI: 10.1016/j.joca.2017.11.001

Source DB:  PubMed          Journal:  Osteoarthritis Cartilage        ISSN: 1063-4584            Impact factor:   6.576


  13 in total

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2.  Analgesic prescribing trends in a national sample of older veterans with osteoarthritis: 2012-2017.

Authors:  Mark Trentalange; Tessa Runels; Andrew Bean; Robert D Kerns; Matthew J Bair; Abraham A Brody; Cynthia A Brandt; Ula Hwang
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3.  Exploring views of orthopaedic surgeons, rheumatologists and general practitioners about osteoarthritis management.

Authors:  Jason A Wallis; Christian J Barton; Natasha K Brusco; Joanne L Kemp; James Sherwood; Kirby Young; Sophie Jennings; Adrian Trivett; Ilana N Ackerman
Journal:  Musculoskeletal Care       Date:  2021-03-12

Review 4.  Risk Factors and Prevention Strategies for Postoperative Opioid Abuse.

Authors:  Shuai Zhao; Fan Chen; Anqi Feng; Wei Han; Yuan Zhang
Journal:  Pain Res Manag       Date:  2019-07-10       Impact factor: 3.037

5.  Association between osteoarthritis and increased risk of dementia: A systemic review and meta-analysis.

Authors:  Adrian Weber; Shing Hung Mak; Francis Berenbaum; Jérémie Sellam; Yong-Ping Zheng; Yifan Han; Chunyi Wen
Journal:  Medicine (Baltimore)       Date:  2019-03       Impact factor: 1.817

6.  The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation.

Authors:  James J Burston; Ana M Valdes; Stephen G Woodhams; Paul I Mapp; Joanne Stocks; David J G Watson; Peter R W Gowler; Luting Xu; Devi R Sagar; Gwen Fernandes; Nadia Frowd; Laura Marshall; Weiya Zhang; Michael Doherty; David A Walsh; Victoria Chapman
Journal:  Pain       Date:  2019-03       Impact factor: 7.926

7.  Future projections of opioid use and cost in patients with chronic osteoarthritis pain in Spain.

Authors:  Javier Rejas-Gutierrez; Antoni Sicras-Mainar; Josep Darbà
Journal:  Ther Adv Musculoskelet Dis       Date:  2021-04-29       Impact factor: 5.346

8.  Opioid prescriptions in patients with osteoarthritis: a population-based cohort study.

Authors:  Jacoline J van den Driest; Dieuwke Schiphof; Marcel de Wilde; Patrick J E Bindels; Johan van der Lei; Sita M A Bierma-Zeinstra
Journal:  Rheumatology (Oxford)       Date:  2020-09-01       Impact factor: 7.580

9.  The effectiveness of Kinesio Taping® for pain management in knee osteoarthritis: a randomized, double-blind, controlled clinical trial.

Authors:  Venta Donec; Raimondas Kubilius
Journal:  Ther Adv Musculoskelet Dis       Date:  2019-08-29       Impact factor: 5.346

Review 10.  Understanding the Molecular Mechanisms Underlying the Pathogenesis of Arthritis Pain Using Animal Models.

Authors:  Jeong-Im Hong; In Young Park; Hyun Ah Kim
Journal:  Int J Mol Sci       Date:  2020-01-14       Impact factor: 5.923

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