Literature DB >> 29129351

Is Serum Methylmalonic Acid a Reliable Biomarker of Vitamin B12 Status in Children with Short Bowel Syndrome: A Case Series.

Lissette Jimenez1, Danielle A Stamm2, Brittany Depaula3, Christopher P Duggan3.   

Abstract

We describe 3 patients with short bowel syndrome who had persistently elevated serum methylmalonic acid (MMA) levels while being treated for vitamin B12 deficiency. Following treatment for presumed small bowel bacterial overgrowth, MMA levels normalized. Among patients with short bowel syndrome, MMA levels may have limited specificity for vitamin B12 deficiency.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  methylmalonic acid; short bowel syndrome; small bowel bacterial overgrowth; vitamin B12 deficiency

Mesh:

Substances:

Year:  2017        PMID: 29129351      PMCID: PMC6029886          DOI: 10.1016/j.jpeds.2017.09.024

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  22 in total

Review 1.  Enteric microbial flora, bacterial overgrowth, and short-bowel syndrome.

Authors:  John K Dibaise; Rosemary J Young; Jon A Vanderhoof
Journal:  Clin Gastroenterol Hepatol       Date:  2006-01       Impact factor: 11.382

2.  Vitamin B12 status, methylmalonic acidemia, and bacterial overgrowth in short bowel syndrome.

Authors:  Timothy A Sentongo; Ruba Azzam; Joel Charrow
Journal:  J Pediatr Gastroenterol Nutr       Date:  2009-04       Impact factor: 2.839

Review 3.  Clinical practice. Vitamin B12 deficiency.

Authors:  Sally P Stabler
Journal:  N Engl J Med       Date:  2013-01-10       Impact factor: 91.245

4.  The use of neomycin in the treatment of methylmalonic aciduria.

Authors:  S E Snyderman; C Sansaricq; P Norton; S V Phansalkar
Journal:  Pediatrics       Date:  1972-12       Impact factor: 7.124

5.  Competition between bacteria and intrinsic factor for vitamin B 12 : implications for vitamin B 12 malabsorption in intestinal bacterial overgrowth.

Authors:  R A Giannella; S A Broitman; N Zamcheck
Journal:  Gastroenterology       Date:  1972-02       Impact factor: 22.682

6.  Gut microbial diversity is reduced and is associated with colonic inflammation in a piglet model of short bowel syndrome.

Authors:  Susan Lapthorne; Prue M Pereira-Fantini; Fiona Fouhy; Guineva Wilson; Sarah L Thomas; Nicole L Dellios; Michelle Scurr; Orla O'Sullivan; R Paul Ross; Catherine Stanton; Gerald F Fitzgerald; Paul D Cotter; Julie E Bines
Journal:  Gut Microbes       Date:  2013-04-02

Review 7.  Small Bowel Bacterial Overgrowth in Children.

Authors:  Agnieszka Sieczkowska; Piotr Landowski; Barbara Kamińska; Carlos Lifschitz
Journal:  J Pediatr Gastroenterol Nutr       Date:  2016-02       Impact factor: 2.839

8.  Natural history of pediatric intestinal failure: initial report from the Pediatric Intestinal Failure Consortium.

Authors:  Robert H Squires; Christopher Duggan; Daniel H Teitelbaum; Paul W Wales; Jane Balint; Robert Venick; Susan Rhee; Debra Sudan; David Mercer; J Andres Martinez; Beth A Carter; Jason Soden; Simon Horslen; Jeffrey A Rudolph; Samuel Kocoshis; Riccardo Superina; Sharon Lawlor; Tamara Haller; Marcia Kurs-Lasky; Steven H Belle
Journal:  J Pediatr       Date:  2012-05-11       Impact factor: 4.406

9.  Multiple micronutrient deficiencies among patients with intestinal failure during and after transition to enteral nutrition.

Authors:  Agozie C Ubesie; Samuel A Kocoshis; Adam G Mezoff; Carol J Henderson; Michael A Helmrath; Conrad R Cole
Journal:  J Pediatr       Date:  2013-08-24       Impact factor: 4.406

10.  Intestinal dysbiosis in children with short bowel syndrome is associated with impaired outcome.

Authors:  Helene Engstrand Lilja; Hugo Wefer; Niklas Nyström; Yigael Finkel; Lars Engstrand
Journal:  Microbiome       Date:  2015-05-04       Impact factor: 14.650

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