| Literature DB >> 29128075 |
Andreas Boldt1, Michael Bitar2, Ulrich Sack2.
Abstract
Primary immunodeficiency diseases are genetic disorders that mostly cause susceptibility to infections and are sometimes associated with autoimmune and malignant diseases. For early detection and management of these diseases, flow cytometric procedures allow an encompassing assessment of cellular phenotypes and cellular functions. State-of-the art cytometry is based today on 8- to 10-color staining and includes an assessment of lineage maturation and functional markers.Entities:
Keywords: B-cell defect; Flow cytometry; Immunodeficiency; Immunophenotyping; T-cell defect
Mesh：
Year: 2017 PMID： 29128075 DOI： 10.1016/j.cll.2017.07.013
Source DB: PubMed Journal: Clin Lab Med ISSN： 0272-2712 Impact factor: 1.935