Literature DB >> 29127566

Monitoring and Treating Metabolic Abnormalities in Patients with Early Psychosis Initiated on Antipsychotic Medications.

Kevin M Bozymski1, Jessica A Whitten2, Mary E Blair2, Ashley M Overley3,4, Carol A Ott2,3,4,5.   

Abstract

Antipsychotic medications carry an established lifetime risk of metabolic syndrome. This retrospective chart review evaluated feasibility of a metabolic monitoring clinical decision support tool (CDST) for weight, lipid, blood glucose, and blood pressure management of 163 clients in an early psychosis outpatient clinic over 2 years. Each parameter had at least 98 (60.1%) clients with a recorded value, the most being documented for weight with 112 (68.7%) clients. CDST adherence ranged from at least 54.3-100% for non-pharmacologic interventions (e.g. clinic counseling, referral to health program or primary care) and at least 33.3-100% for pharmacologic interventions (e.g. metformin). Though no baseline cardiometabolic abnormalities were identified, dyslipidemia and obesity were later found in 37 (22.7%) and 35 (21.5%) clients, respectively. Only 14 (8.6%) clients were prescribed medications for cardiometabolic abnormalities by psychiatrists in the clinic. Increasing focus on physical health is needed to better this population's long-term prognosis.

Entities:  

Keywords:  Antipsychotic; Clinical decision support tool; First episode psychosis; Metabolic syndrome

Mesh:

Substances:

Year:  2017        PMID: 29127566     DOI: 10.1007/s10597-017-0203-y

Source DB:  PubMed          Journal:  Community Ment Health J        ISSN: 0010-3853


  41 in total

1.  Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report.

Authors: 
Journal:  Circulation       Date:  2002-12-17       Impact factor: 29.690

2.  A survey of psychiatrists' attitudes towards the physical examination.

Authors:  Jonathan Murray; Sarah Baillon; Janet Bruce; Latha Velayudhan
Journal:  J Ment Health       Date:  2015-07-17

3.  The NAVIGATE Program for First-Episode Psychosis: Rationale, Overview, and Description of Psychosocial Components.

Authors:  Kim T Mueser; David L Penn; Jean Addington; Mary F Brunette; Susan Gingerich; Shirley M Glynn; David W Lynde; Jennifer D Gottlieb; Piper Meyer-Kalos; Susan R McGurk; Corinne Cather; Sylvia Saade; Delbert G Robinson; Nina R Schooler; Robert A Rosenheck; John M Kane
Journal:  Psychiatr Serv       Date:  2015-03-16       Impact factor: 3.084

4.  National lipid association recommendations for patient-centered management of dyslipidemia: part 1--full report.

Authors:  Terry A Jacobson; Matthew K Ito; Kevin C Maki; Carl E Orringer; Harold E Bays; Peter H Jones; James M McKenney; Scott M Grundy; Edward A Gill; Robert A Wild; Don P Wilson; W Virgil Brown
Journal:  J Clin Lipidol       Date:  2015-04-07       Impact factor: 4.766

Review 5.  The 2009 schizophrenia PORT psychopharmacological treatment recommendations and summary statements.

Authors:  Robert W Buchanan; Julie Kreyenbuhl; Deanna L Kelly; Jason M Noel; Douglas L Boggs; Bernard A Fischer; Seth Himelhoch; Beverly Fang; Eunice Peterson; Patrick R Aquino; William Keller
Journal:  Schizophr Bull       Date:  2009-12-02       Impact factor: 9.306

6.  Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents.

Authors:  Christoph U Correll; Peter Manu; Vladimir Olshanskiy; Barbara Napolitano; John M Kane; Anil K Malhotra
Journal:  JAMA       Date:  2009-10-28       Impact factor: 56.272

7.  Premature Mortality Among Adults With Schizophrenia in the United States.

Authors:  Mark Olfson; Tobias Gerhard; Cecilia Huang; Stephen Crystal; T Scott Stroup
Journal:  JAMA Psychiatry       Date:  2015-12       Impact factor: 21.596

8.  A 12-week randomized clinical trial to evaluate metabolic changes in drug-naive, first-episode psychosis patients treated with haloperidol, olanzapine, or risperidone.

Authors:  Rocio Perez-Iglesias; Benedicto Crespo-Facorro; Jose Antonio Amado; Maria Teresa Garcia-Unzueta; Maria Luz Ramirez-Bonilla; Cesar Gonzalez-Blanch; Obdulia Martinez-Garcia; Jose Luis Vazquez-Barquero
Journal:  J Clin Psychiatry       Date:  2007-11       Impact factor: 4.384

Review 9.  Diabetes, psychotic disorders and antipsychotic therapy: a consensus statement.

Authors:  Tim J R Lambert; Leon H Chapman
Journal:  Med J Aust       Date:  2004-11-15       Impact factor: 7.738

10.  Recent advances in understanding and mitigating adipogenic and metabolic effects of antipsychotic drugs.

Authors:  Julia M Gohlke; Emily J Dhurandhar; Christoph U Correll; Elaine H Morrato; John W Newcomer; Gary Remington; Henry A Nasrallah; Stephen Crystal; Ginger Nicol; David B Allison
Journal:  Front Psychiatry       Date:  2012-06-28       Impact factor: 4.157

View more
  4 in total

Review 1.  Weight and body mass index increase in children and adolescents exposed to antipsychotic drugs in non-interventional settings: a meta-analysis and meta-regression.

Authors:  Marco Pozzi; Roberta Ida Ferrentino; Giulia Scrinzi; Cristina Scavone; Annalisa Capuano; Sonia Radice; Maria Nobile; Pietro Formisano; Emilio Clementi; Carmela Bravaccio; Carla Carnovale; Simone Pisano
Journal:  Eur Child Adolesc Psychiatry       Date:  2020-07-02       Impact factor: 4.785

2.  The role of pharmacy in the management of cardiometabolic risk, metabolic syndrome and related diseases in severe mental illness: a mixed-methods systematic literature review.

Authors:  Dolly Sud; Eileen Laughton; Robyn McAskill; Eleanor Bradley; Ian Maidment
Journal:  Syst Rev       Date:  2021-03-31

3.  Antipsychotic Drug-Induced Increases in Peripheral Catecholamines are Associated With Glucose Intolerance.

Authors:  Heidi N Boyda; Michelle Pham; Joyce Huang; Amanzo A Ho; Ric M Procyshyn; Jessica W Y Yuen; William G Honer; Alasdair M Barr
Journal:  Front Pharmacol       Date:  2022-02-15       Impact factor: 5.810

4.  Gait Alterations in the Prediction of Metabolic Syndrome in Patients With Schizophrenia: A Pilot Study With PODOSmart ® Insoles.

Authors:  Dimitris Efthymiou; Dimitrios X Zekakos; Evangelia Papatriantafyllou; Efthimis Ziagkas; Alexandros N Petrelis; Emilia Vassilopoulou
Journal:  Front Psychiatry       Date:  2022-01-27       Impact factor: 4.157

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.