Harshit Garg1, Sandeep Aggarwal2, Mahesh Chandra Misra3, Pratyusha Priyadarshini4, Ashish Swami5, Lokesh Kashyap6, Richa Jaiswal7. 1. Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India. Electronic address: hgarg3108@gmail.com. 2. Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India. Electronic address: sandeep_aiims@yahoo.co.in. 3. Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India. Electronic address: mcmisra@gmail.com. 4. Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India. Electronic address: pratyushaaiims@yahoo.co.in. 5. Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India. Electronic address: drashishswami10@gmail.com. 6. Department of Anaesthesiology and Critical Care, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India. Electronic address: lokeshkashyap@yahoo.com. 7. Department of Dietetics, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India. Electronic address: richajas@yahoo.com.
Abstract
INTRODUCTION: Few studies have addressed the mid to long term impact of Laparoscopic Sleeve Gastrectomy (LSG) on weight loss and obesity associated co-morbidities, particularly in Indian population. The aim of this study is to assess the efficacy of LSG in morbid obesity over 3-7 years follow up. MATERIALS AND METHODS: Data of all patients who underwent LSG between January 2008 and March 2015 and completed their at least 1 year follow up till March 2016 was retrospectively reviewed using a prospectively collected database. RESULTS: 424 patients undergoing primary LSG were included. The mean age (±2SD) was 39.8 ± 22.5 years and the mean Body Mass Index (BMI) (±2SD) was 46.67 ± 15.8 kg/m2. 124 patients (29.2%) were super-obese (BMI >50 kg/m2). The percentage follow-up at 1 year, 3 years, 5 years and 7 years was 78.3%, 66.7%, 42.3% and 38.4% respectively. The mean percentage Excess weight Loss (%EWL) (±2SD) at 1year, 3years, 5years, and 7years was 71.8 (±50.5%), 64.95% (±41.8%), 61.7% (±46.2%) and 57.15% (±50.2%) respectively. The preoperative BMI significantly correlated with %EWL at 5 year (r2 = 0.107, p = 0.018). The overall complication rate was 5.8%. Early complications included staple line leak (1.2%), bleeding (1.2%), deep venous thrombosis (0.4%) and 30-day mortality (0.21%). Late complications included stricture formation (0.21%) and new onset Gastro-esophageal Reflux Disease (GERD) (2.8%).At 5 years, 83.3% of diabetic patients showed remission while rest showed improvement in glycemic control with decrease in dosage. 69.3% patients showed improvement in hypertension, 100% patients showed improvement in Obstructive Sleep Apnea Syndrome, 75% patients showed improvement in hypothyroidism after surgery. GERD resolved in 62.8% patients while worsened in 11.4% patients. CONCLUSIONS: LSG has durable weight loss at 5 year with %EWL of 61% and significant resolution of obesity associated co-morbidities.
INTRODUCTION: Few studies have addressed the mid to long term impact of Laparoscopic Sleeve Gastrectomy (LSG) on weight loss and obesity associated co-morbidities, particularly in Indian population. The aim of this study is to assess the efficacy of LSG in morbid obesity over 3-7 years follow up. MATERIALS AND METHODS: Data of all patients who underwent LSG between January 2008 and March 2015 and completed their at least 1 year follow up till March 2016 was retrospectively reviewed using a prospectively collected database. RESULTS: 424 patients undergoing primary LSG were included. The mean age (±2SD) was 39.8 ± 22.5 years and the mean Body Mass Index (BMI) (±2SD) was 46.67 ± 15.8 kg/m2. 124 patients (29.2%) were super-obese (BMI >50 kg/m2). The percentage follow-up at 1 year, 3 years, 5 years and 7 years was 78.3%, 66.7%, 42.3% and 38.4% respectively. The mean percentage Excess weight Loss (%EWL) (±2SD) at 1year, 3years, 5years, and 7years was 71.8 (±50.5%), 64.95% (±41.8%), 61.7% (±46.2%) and 57.15% (±50.2%) respectively. The preoperative BMI significantly correlated with %EWL at 5 year (r2 = 0.107, p = 0.018). The overall complication rate was 5.8%. Early complications included staple line leak (1.2%), bleeding (1.2%), deep venous thrombosis (0.4%) and 30-day mortality (0.21%). Late complications included stricture formation (0.21%) and new onset Gastro-esophageal Reflux Disease (GERD) (2.8%).At 5 years, 83.3% of diabeticpatients showed remission while rest showed improvement in glycemic control with decrease in dosage. 69.3% patients showed improvement in hypertension, 100% patients showed improvement in Obstructive Sleep Apnea Syndrome, 75% patients showed improvement in hypothyroidism after surgery. GERD resolved in 62.8% patients while worsened in 11.4% patients. CONCLUSIONS: LSG has durable weight loss at 5 year with %EWL of 61% and significant resolution of obesity associated co-morbidities.
Authors: Aurora Gil-Rendo; José Ramón Muñoz-Rodríguez; Francisco Domper Bardají; Bruno Menchén Trujillo; Fernando Martínez-de Paz; María Del Prado Caro González; Irene Arjona Medina; Jesús Martín Fernández Journal: Obes Surg Date: 2019-11 Impact factor: 4.129
Authors: Giovanna Pavone; Nicola Tartaglia; Alessandro Porfido; Piercarmine Panzera; Mario Pacilli; Antonio Ambrosi Journal: Ann Med Surg (Lond) Date: 2022-04-05