Literature DB >> 29121027

Age-related macular degeneration foils drugmakers.

Elie Dolgin.   

Abstract

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Year:  2017        PMID： 29121027     DOI： 10.1038/nbt1117-1000

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  4 in total

1.  Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration.

Authors:  Brian L Yaspan; David F Williams; Frank G Holz; Carl D Regillo; Zhengrong Li; Amy Dressen; Menno van Lookeren Campagne; Kha N Le; Robert R Graham; Tatiana Beres; Tushar R Bhangale; Lee A Honigberg; Ashley Smith; Erin C Henry; Carole Ho; Erich C Strauss
Journal:  Sci Transl Med       Date:  2017-06-21       Impact factor: 17.956

2.  Stem cell therapy clears first hurdle in AMD.

Authors:  Cormac Sheridan
Journal:  Nat Biotechnol       Date:  2014-12       Impact factor: 54.908

3.  Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome.

Authors:  Bradley D Gelfand; Charles B Wright; Younghee Kim; Tetsuhiro Yasuma; Reo Yasuma; Shengjian Li; Benjamin J Fowler; Ana Bastos-Carvalho; Nagaraj Kerur; Annette Uittenbogaard; Youn Seon Han; Dingyuan Lou; Mark E Kleinman; W Hayes McDonald; Gabriel Núñez; Philippe Georgel; Joshua L Dunaief; Jayakrishna Ambati
Journal:  Cell Rep       Date:  2015-06-11       Impact factor: 9.423

4.  Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity.

Authors:  Benjamin J Fowler; Bradley D Gelfand; Younghee Kim; Nagaraj Kerur; Valeria Tarallo; Yoshio Hirano; Shoba Amarnath; Daniel H Fowler; Marta Radwan; Mark T Young; Keir Pittman; Paul Kubes; Hitesh K Agarwal; Keykavous Parang; David R Hinton; Ana Bastos-Carvalho; Shengjian Li; Tetsuhiro Yasuma; Takeshi Mizutani; Reo Yasuma; Charles Wright; Jayakrishna Ambati
Journal:  Science       Date:  2014-11-21       Impact factor: 47.728
  4 in total
  7 in total

1.  Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration.

Authors:  Gulpreet Kaur; Li Xuan Tan; Gurugirijha Rathnasamy; Nilsa La Cunza; Colin J Germer; Kimberly A Toops; Marie Fernandes; Timothy A Blenkinsop; Aparna Lakkaraju
Journal:  Proc Natl Acad Sci U S A       Date:  2018-08-20       Impact factor: 11.205

Review 2.  Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions.

Authors:  Benjamin J Kim; Dimitrios C Mastellos; Yafeng Li; Joshua L Dunaief; John D Lambris
Journal:  Prog Retin Eye Res       Date:  2020-12-13       Impact factor: 19.704

Review 3.  Negative Regulators of Angiogenesis, Ocular Vascular Homeostasis, and Pathogenesis and Treatment of Exudative AMD.

Authors:  Mitra Farnoodian; Christine M Sorenson; Nader Sheibani
Journal:  J Ophthalmic Vis Res       Date:  2018 Oct-Dec

Review 4.  Be on Target: Strategies of Targeting Alternative and Lectin Pathway Components in Complement-Mediated Diseases.

Authors:  József Dobó; Andrea Kocsis; Péter Gál
Journal:  Front Immunol       Date:  2018-08-08       Impact factor: 7.561

Review 5.  Complement system and age-related macular degeneration: drugs and challenges.

Authors:  Jiali Wu; Xiaodong Sun
Journal:  Drug Des Devel Ther       Date:  2019-07-19       Impact factor: 4.162

6.  Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.

Authors:  Kenneth J Katschke; Hongkang Xi; Christian Cox; Tom Truong; Yann Malato; Wyne P Lee; Brent McKenzie; Rommel Arceo; Jianhua Tao; Linda Rangell; Mike Reichelt; Lauri Diehl; Justin Elstrott; Robby M Weimer; Menno van Lookeren Campagne
Journal:  Sci Rep       Date:  2018-05-09       Impact factor: 4.379

7.  Mitochondria-dependent phase separation of disease-relevant proteins drives pathological features of age-related macular degeneration.

Authors:  Nilsa La Cunza; Li Xuan Tan; Thushara Thamban; Colin J Germer; Gurugirijha Rathnasamy; Kimberly A Toops; Aparna Lakkaraju
Journal:  JCI Insight       Date:  2021-05-10
  7 in total

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