Literature DB >> 29119603

Phototherapy is commonly used for neonatal jaundice but greater control is needed to avoid toxicity in the most vulnerable infants.

Khalaf Mreihil1,2, Jūratė Šaltytė Benth2,3, Hans Jørgen Stensvold2,4, Britt Nakstad1,2, Thor Willy Ruud Hansen2,4.   

Abstract

AIM: Limited information is available about how guidelines on phototherapy for neonatal jaundice are applied in practice and toxicity is a concern. We studied the use of phototherapy in relation to birthweight and gestational age (GA) in Norwegian neonatal intensive care units (NICUs).
METHODS: The study population was all 5382 infants admitted to the 21 NICUs in Norway between September 1, 2013 and August 31, 2014. Data were recorded daily in the Norwegian Neonatal Network database and anonymised data on patient characteristics, diagnoses, duration, the ages at the start and discontinuation of phototherapy were analysed.
RESULTS: More than a quarter (26.6%) of all infants admitted to Norwegian NICUs during the study period received phototherapy. The use of phototherapy was inversely related to GA and birthweight. More than 80% of the preterm infants under 28 weeks of GA received phototherapy. The duration was significantly longer in the lowest birthweight and GA groups and decreased with increasing birthweight and GA.
CONCLUSION: Phototherapy is proved to be a strong candidate for the most common therapeutic modality in NICU infants. However, in the light of reported toxicity in the smallest, most vulnerable infants, we recommend increased emphasis on quality control. ©2017 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Clinical guidelines; Hyperbilirubinaemia; Neonatal intensive care unit; Neonatal jaundice; Phototherapy

Mesh:

Year:  2017        PMID: 29119603     DOI: 10.1111/apa.14141

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  6 in total

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2.  Exploration of the pathogenic factors of neonatal jaundice and the clinical effect of blue phototherapy.

Authors:  Bixin Yu; Fangqi Hu
Journal:  Am J Transl Res       Date:  2021-06-15       Impact factor: 4.060

3.  An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice.

Authors:  Yan Jiao; Yuting Jin; Huanhuan Meng; Meizhang Wen
Journal:  Exp Ther Med       Date:  2018-06-21       Impact factor: 2.447

4.  Should transcutaneous bilirubin be measured in preterm infants receiving phototherapy? The relationship between transcutaneous and total serum bilirubin in preterm infants with and without phototherapy.

Authors:  Christian V Hulzebos; Deirdre E Vader-van Imhoff; Arend F Bos; Peter H Dijk
Journal:  PLoS One       Date:  2019-06-14       Impact factor: 3.240

5.  Effectiveness of FIBEROPTIC phototherapy compared to conventional phototherapy in treating HYPERBILIRUBINEMIA amongst term neonates: a randomized controlled trial.

Authors:  Helvi N Joel; Deborah N Mchaile; Rune N Philemon; Ronald M Mbwasi; Levina Msuya
Journal:  BMC Pediatr       Date:  2021-01-11       Impact factor: 2.125

6.  The Turkish Neonatal Jaundice Online Registry: A national root cause analysis.

Authors:  Omer Erdeve; Emel Okulu; Ozgur Olukman; Dilek Ulubas; Gokhan Buyukkale; Fatma Narter; Gaffari Tunc; Begum Atasay; Nazli Dilay Gultekin; Saadet Arsan; Esin Koc
Journal:  PLoS One       Date:  2018-02-23       Impact factor: 3.240

  6 in total

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