Literature DB >> 29119506

Complexity of Biochemical and Genetic Responses Reduced Using Simple Theoretical Models.

Kumar Selvarajoo1.   

Abstract

Living systems are known to behave in a complex and sometimes unpredictable manner. Humans, for a very long time, have been intrigued by nature, and have attempted to understand biological processes and mechanisms using numerous experimental and mathematical techniques. In this chapter, we will look at simple theoretical models, using both linear and nonlinear differential equations, that realistically capture complex biochemical and genetic responses of living cells. Even for cases where cellular behaviors are stochastic, as for single-cell responses, randomness added to well-defined deterministic models has elegantly been shown to be useful. The data collectively present evidence for further exploration of the self-organizing rules and laws of living matter.

Entities:  

Keywords:  Biological networks; Modeling; Nonlinear dynamics; Oscillation; Systems biology

Mesh:

Year:  2018        PMID: 29119506     DOI: 10.1007/978-1-4939-7456-6_9

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  3 in total

1.  Defining rules for cancer cell proliferation in TRAIL stimulation.

Authors:  William Deveaux; Kentaro Hayashi; Kumar Selvarajoo
Journal:  NPJ Syst Biol Appl       Date:  2019-02-15

Review 2.  Order Through Disorder: The Characteristic Variability of Systems.

Authors:  Yaron Ilan
Journal:  Front Cell Dev Biol       Date:  2020-03-20

3.  Searching for simple rules in Pseudomonas aeruginosa biofilm formation.

Authors:  William Deveaux; Kumar Selvarajoo
Journal:  BMC Res Notes       Date:  2019-11-21
  3 in total

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