Literature DB >> 29119435

Guidelines to Compose an Ideal Bacteriophage Cocktail.

Maia Merabishvili1, Jean-Paul Pirnay2, Daniel De Vos2.   

Abstract

Correctly designed bacteriophage therapeutics are the cornerstone for a successful outcome of bacteriophage therapy. Here we overview strategies on how to choose bacteriophages and their bacterial hosts at different steps of a bacteriophage cocktail development in order to comply with all quality and safety requirements based on the already existing essentially empirical experience in bacteriophage therapy and current accomplishments in modern biomedical sciences. A modification of the classic Appelmans' method (1922) to assess stability of bacteriophage activity in liquid media is presented in order to improve the overall performance of therapeutic bacteriophages individually and collectively in the cocktail.

Entities:  

Keywords:  Adaptation of bacteriophages; Bacteria and bacteriophage of choice; Bacteriophage compatibility; Bacteriophage therapeutics; Host range; Virulent bacteriophages

Mesh：

Year:  2018        PMID： 29119435     DOI： 10.1007/978-1-4939-7395-8_9

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  32 in total

Review 1.  Bacteriophages and their potential for treatment of gastrointestinal diseases.

Authors:  Yi Duan; Ry Young; Bernd Schnabl
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2021-11-15       Impact factor: 46.802

Review 2.  Biological foundations of successful bacteriophage therapy.

Authors:  Carola Venturini; Aleksandra Petrovic Fabijan; Alicia Fajardo Lubian; Stefanie Barbirz; Jonathan Iredell
Journal:  EMBO Mol Med       Date:  2022-05-27       Impact factor: 14.260

3.  Development of an Anti-Acinetobacter baumannii Biofilm Phage Cocktail: Genomic Adaptation to the Host.

Authors:  L Blasco; I Bleriot; M González de Aledo; L Fernández-García; O Pacios; H Oliveira; M López; C Ortiz-Cartagena; F Fernández-Cuenca; Á Pascual; L Martínez-Martínez; J Pachón; J Azeredo; M Tomás
Journal:  Antimicrob Agents Chemother       Date:  2022-01-18       Impact factor: 5.938

4.  Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strains.

Authors:  Christine Rohde; Grégory Resch; Jean-Paul Pirnay; Bob G Blasdel; Laurent Debarbieux; Daniel Gelman; Andrzej Górski; Ronen Hazan; Isabelle Huys; Elene Kakabadze; Małgorzata Łobocka; Alice Maestri; Gabriel Magno de Freitas Almeida; Khatuna Makalatia; Danish J Malik; Ivana Mašlaňová; Maia Merabishvili; Roman Pantucek; Thomas Rose; Dana Štveráková; Hilde Van Raemdonck; Gilbert Verbeken; Nina Chanishvili
Journal:  Viruses       Date:  2018-04-05       Impact factor: 5.048

5.  Adapted Bacteriophages for Treating Urinary Tract Infections.

Authors:  Aleksandre Ujmajuridze; Nina Chanishvili; Marina Goderdzishvili; Lorenz Leitner; Ulrich Mehnert; Archil Chkhotua; Thomas M Kessler; Wilbert Sybesma
Journal:  Front Microbiol       Date:  2018-08-07       Impact factor: 5.640

6.  Isolation of A Novel Bacillus thuringiensis Phage Representing A New Phage Lineage and Characterization of Its Endolysin.

Authors:  Yihui Yuan; Qin Peng; Shuo Yang; Shaowen Zhang; Yajuan Fu; Yan Wu; Meiying Gao
Journal:  Viruses       Date:  2018-11-06       Impact factor: 5.048

Review 7.  Enhancing Whole Phage Therapy and Their Derived Antimicrobial Enzymes through Complex Formulation.

Authors:  Callum J Cooper; Shazeeda Koonjan; Anders S Nilsson
Journal:  Pharmaceuticals (Basel)       Date:  2018-04-19

8.  Parallel Evolution of Host-Attachment Proteins in Phage PP01 Populations Adapting to Escherichia coli O157:H7.

Authors:  Chidiebere Akusobi; Benjamin K Chan; Elizabeth S C P Williams; John E Wertz; Paul E Turner
Journal:  Pharmaceuticals (Basel)       Date:  2018-06-20

Review 9.  Bacteriophage-Mediated Control of Phytopathogenic Xanthomonads: A Promising Green Solution for the Future.

Authors:  Emilio Stefani; Aleksa Obradović; Katarina Gašić; Irem Altin; Ildikó K Nagy; Tamás Kovács
Journal:  Microorganisms       Date:  2021-05-13

10.  Design of a Broad-Range Bacteriophage Cocktail That Reduces Pseudomonas aeruginosa Biofilms and Treats Acute Infections in Two Animal Models.

Authors:  Francesca Forti; Dwayne R Roach; Marco Cafora; Maria E Pasini; David S Horner; Ersilia V Fiscarelli; Martina Rossitto; Lisa Cariani; Federica Briani; Laurent Debarbieux; Daniela Ghisotti
Journal:  Antimicrob Agents Chemother       Date:  2018-05-25       Impact factor: 5.191
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