Sooyeoun You1, Hye-Jin Moon1,2, So Young Do1, Yun-Kwok Wing3, Jun-Sang Sunwoo4, Ki-Young Jung5, Yong Won Cho1. 1. Department of Neurology, Keimyung University School of Medicine, Daegu, Republic of Korea. 2. Department of Neurology, School of Medicine, Soonchunhyang University, Bucheon, Republic of Korea. 3. Department of Psychiatry, Shatin Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China. 4. Department of Neurology, School of Medicine, Soonchunhyang University, Seoul, Republic of Korea. 5. Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Abstract
STUDY OBJECTIVES: REM sleep behavior disorder (RBD) is a parasomnia that is commonly associated with neurodegenerative disorders. We aimed to validate the Hong Kong version of the self-reported RBD questionnaire (RBDQ-HK) with the Korean version (RBDQ-KR) and to investigate its clinical usefulness. METHODS: One-hundred five patients with RBD and 105 age- and sex-matched controls were enrolled. Thirty were randomly selected for a retest with the questionnaire after 2 to 4 weeks without any treatment. Receiver operating characteristic curve and exploratory factor analysis were used to evaluate the scale, which had a score ranging from 0 to 100. RESULTS: There was no difference in mean age and sex in patients with RBD and control subjects. Patients with RBD had a significantly higher total RBDQ-KR score than the control group (P < .001). The RBDQ-KR demonstrated high sensitivity (93.3%), specificity (89.5%), positive predictive value (89.9%), and negative predictive value (93.1%). Cronbach α coefficient for internal consistency of the total score of the RBDQ-KR was 0.9, which shows high reliability. Exploratory factor analysis showed two components, dream-related and behavioral factors, consistent with the main clinical features of RBD. Based on the results, the best cutoff for the total score ranging from 0 to 100 was at 18/19 and for factor 2 ranging from 0 to 75 was at 11. CONCLUSIONS: This study showed RBDQ-KR is a valid and reliable questionnaire for RBD symptoms and severity in Korea. It serves as an effective tool to identify patients with RBD and to facilitate future clinical and research studies.
STUDY OBJECTIVES:REM sleep behavior disorder (RBD) is a parasomnia that is commonly associated with neurodegenerative disorders. We aimed to validate the Hong Kong version of the self-reported RBD questionnaire (RBDQ-HK) with the Korean version (RBDQ-KR) and to investigate its clinical usefulness. METHODS: One-hundred five patients with RBD and 105 age- and sex-matched controls were enrolled. Thirty were randomly selected for a retest with the questionnaire after 2 to 4 weeks without any treatment. Receiver operating characteristic curve and exploratory factor analysis were used to evaluate the scale, which had a score ranging from 0 to 100. RESULTS: There was no difference in mean age and sex in patients with RBD and control subjects. Patients with RBD had a significantly higher total RBDQ-KR score than the control group (P < .001). The RBDQ-KR demonstrated high sensitivity (93.3%), specificity (89.5%), positive predictive value (89.9%), and negative predictive value (93.1%). Cronbach α coefficient for internal consistency of the total score of the RBDQ-KR was 0.9, which shows high reliability. Exploratory factor analysis showed two components, dream-related and behavioral factors, consistent with the main clinical features of RBD. Based on the results, the best cutoff for the total score ranging from 0 to 100 was at 18/19 and for factor 2 ranging from 0 to 75 was at 11. CONCLUSIONS: This study showed RBDQ-KR is a valid and reliable questionnaire for RBD symptoms and severity in Korea. It serves as an effective tool to identify patients with RBD and to facilitate future clinical and research studies.
Authors: Jun Sang Sunwoo; Young Ji Kim; Jung Ick Byun; Tae Joon Kim; Jin Sun Jun; Soon Tae Lee; Keun Hwa Jung; Kyung Il Park; Kon Chu; Manho Kim; Sang Kun Lee; Han Joon Kim; Carlos H Schenck; Ki Young Jung Journal: J Clin Neurol Date: 2020-04 Impact factor: 3.077
Authors: Gyeong Seon Choi; Ji Young Yun; Sungeun Hwang; Song E Kim; Jeong-Yeon Kim; Chang-Hwan Im; Hyang Woon Lee Journal: J Clin Med Date: 2021-11-27 Impact factor: 4.241