| Literature DB >> 29117544 |
Klaus-Armin Nave1, Iva D Tzvetanova2, Stefanie Schirmeier3.
Abstract
In Drosophila, neuronal mitochondria that lack OXPHOS generate ROS-protective fatty acids and lipid droplets in associated glia. In this issue, Liu et al. (2017) demonstrate that neuronal lipid synthesis is driven by the glial lactate shuttle. This lipoprotein-dependent deposition of lipids may be at the origin of glial specializations evolving in vertebrates.Entities:
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Year: 2017 PMID： 29117544 DOI： 10.1016/j.cmet.2017.10.011
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287