| Literature DB >> 29114158 |
Selvaraj Stephen1, Jothimani Pradeep1, Velmurugan Anitharaj1, Venkatraman Janarthanam2.
Abstract
Our objective is to study the seroprevalence of toxoplasmosis in the voluntary blood donors of Puducherry and surrounding districts of Tamil Nadu. A total of 275 healthy blood donors were screened for the presence of IgM and IgG antibodies to Toxoplasma gondii by ELISA test. Donor samples positive for IgM and/or IgG antibodies to T. gondii were subjected to IgG avidity ELISA. While, 54 out of 275 donors had IgG antibodies (19.66%), only one donor had IgM (0.36%) along with IgG. Among 54 IgG positive donors, only two had low avidity (3.7%), indicating recent exposure to the protozoa. Feasibility and cost effectiveness studies should be conducted throughout India to decide regarding screening of blood donors for toxoplasmosis.Entities:
Keywords: Avidity; Blood donors; IgG ELISA; IgM ELISA; Toxoplasma gondii
Year: 2017 PMID: 29114158 PMCID: PMC5660049 DOI: 10.1007/s12639-017-0949-8
Source DB: PubMed Journal: J Parasit Dis ISSN: 0971-7196