Lauro Ângelo Gonçalves de Moraes1,2, Érica Barbosa Felestrino3, Renata de Almeida Barbosa Assis3, Diogo Matos1, Joubert de Castro Lima2, Leandro de Araújo Lima4, Nalvo Franco Almeida5, João Carlos Setubal6, Camila Carrião Machado Garcia3,7, Leandro Marcio Moreira1,3,7. 1. Laboratório Multiusuário de Bioinformática, Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG 35400-000, Brazil. 2. Departamento de Computação, Universidade Federal de Ouro Preto, Ouro Preto, MG 35400-000, Brazil. 3. Núcleo de Pesquisas em Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG 35400-000, Brazil. 4. Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA. 5. Faculdade de Computação, Universidade Federal do Mato Grosso do Sul, Mato Grosso do Sul, MS 79070-900, Brazil. 6. Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, Brazil. 7. Departamento de Ciências Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, MG 34500-000, Brazil.
Abstract
Motivation: Information about metabolic pathways in a comparative context is one of the most powerful tool to help the understanding of genome-based differences in phenotypes among organisms. Although several platforms exist that provide a wealth of information on metabolic pathways of diverse organisms, the comparison among organisms using metabolic pathways is still a difficult task. Results: We present TabPath (Tables for Metabolic Pathway), a web-based tool to facilitate comparison of metabolic pathways in genomes based on KEGG. From a selection of pathways and genomes of interest on the menu, TabPath generates user-friendly tables that facilitate analysis of variations in metabolism among the selected organisms. Availability and implementation: TabPath is available at http://200.239.132.160:8686. Contact: lmmorei@gmail.com.
Motivation: Information about metabolic pathways in a comparative context is one of the most powerful tool to help the understanding of genome-based differences in phenotypes among organisms. Although several platforms exist that provide a wealth of information on metabolic pathways of diverse organisms, the comparison among organisms using metabolic pathways is still a difficult task. Results: We present TabPath (Tables for Metabolic Pathway), a web-based tool to facilitate comparison of metabolic pathways in genomes based on KEGG. From a selection of pathways and genomes of interest on the menu, TabPath generates user-friendly tables that facilitate analysis of variations in metabolism among the selected organisms. Availability and implementation: TabPath is available at http://200.239.132.160:8686. Contact: lmmorei@gmail.com.