Manhal Izzy1, Mindy Lee2, Krysta Johns-Keating2, Faraj Kargoli2, Steven Beckoff2, Kwang Chun3, Aaron Tokayer2. 1. Division of Gastroenterology and Liver Diseases, Montefiore Medical Center, The Albert Einstein College of Medicine, Bronx, NY, United States. Electronic address: mizzy@montefiore.org. 2. Division of Gastroenterology and Liver Diseases, Montefiore Medical Center, The Albert Einstein College of Medicine, Bronx, NY, United States. 3. Division of Nuclear Medicine, Montefiore Medical Center, The Albert Einstein College of Medicine, Bronx, NY, United States.
Abstract
AIM: To investigate the association between glycemic control represented by glycated hemoglobin (HbA1c) level and the value of 4-h gastric retention on nuclear scan. METHODS: We retrospectively reviewed records of diabetic patients who had 4-h nuclear gastric emptying study, with documented 4-h retention value, between January 1st, 2002 and July 30th, 2014 and had HbA1C level close to the time of the study. We divided our cohort into patients with good glycemic control (HbA1C <7, group A), fair control (7-9, group B), and poor control (>9, group C). The 4-h retention value and symptoms were compared between the 3 groups. RESULTS: Our cohort included 299 patients; mean age was 59 ± 14. The median interval between performing gastric emptying study and measuring HbA1C was 41 days. There were 94 patients in group A (HbA1C 6.1 ± 0.4), 131 patients in group B (HbA1C 7.9 ± 0.5), and 74 patients in group C (HbA1C 10.9 ± 1.6). The mean gastric retention value was different between the three study groups, 8.3% ±17, 11.5% ±19, and 14.4% ±21, respectively (P = .03). CONCLUSION: This is the first study to show that HbA1C level is significantly associated with the 4-h retention value on nuclear gastric emptying scan.
AIM: To investigate the association between glycemic control represented by glycated hemoglobin (HbA1c) level and the value of 4-h gastric retention on nuclear scan. METHODS: We retrospectively reviewed records of diabeticpatients who had 4-h nuclear gastric emptying study, with documented 4-h retention value, between January 1st, 2002 and July 30th, 2014 and had HbA1C level close to the time of the study. We divided our cohort into patients with good glycemic control (HbA1C <7, group A), fair control (7-9, group B), and poor control (>9, group C). The 4-h retention value and symptoms were compared between the 3 groups. RESULTS: Our cohort included 299 patients; mean age was 59 ± 14. The median interval between performing gastric emptying study and measuring HbA1C was 41 days. There were 94 patients in group A (HbA1C 6.1 ± 0.4), 131 patients in group B (HbA1C 7.9 ± 0.5), and 74 patients in group C (HbA1C 10.9 ± 1.6). The mean gastric retention value was different between the three study groups, 8.3% ±17, 11.5% ±19, and 14.4% ±21, respectively (P = .03). CONCLUSION: This is the first study to show that HbA1C level is significantly associated with the 4-h retention value on nuclear gastric emptying scan.
Authors: Michael Camilleri; Braden Kuo; Linda Nguyen; Vida M Vaughn; Jessica Petrey; Katarina Greer; Rena Yadlapati; Thomas L Abell Journal: Am J Gastroenterol Date: 2022-06-03 Impact factor: 12.045
Authors: Ryan Jalleh; Chinmay S Marathe; Christopher K Rayner; Karen L Jones; Michael Horowitz Journal: Curr Diab Rep Date: 2019-12-02 Impact factor: 4.810