Literature DB >> 29109576

Baseline Competency Assessment of Pharmacists Prescribing and Managing Vancomycin Therapy in the Regina Qu'Appelle Health Region.

Kirsten Tangedal1, Jennifer Bolt2, Suzanne Len3, Ali Bell4.   

Abstract

BACKGROUND: Pharmacists in the Regina Qu'Appelle Health Region (RQHR), Saskatchewan, independently dose, monitor, and adjust vancomycin therapy. No framework exists for ongoing competency assessment of pharmacists.
OBJECTIVES: The primary objective was to determine pharmacists' overall level of competency for all components of the vancomycin prescribing procedure. The secondary objectives were to determine competency for individual prescribing phases, to stratify overall competency in relation to pharmacist and patient factors, and to identify the 3 most frequent errors.
METHODS: A retrospective chart audit was performed of patients who received a prescription for vancomycin between November 1, 2015, and January 31, 2016. Patients were included if they received pharmacist-prescribed vancomycin as an inpatient or outpatient of an RQHR facility. Patients under the care of a pediatrician, those receiving vancomycin for surgical prophylaxis or via any route other than the IV route, and those whose vancomycin was prescribed by a current pharmacy resident were excluded. A rubric was created that assigned a numeric value for the appropriate completion of various procedure criteria.
RESULTS: A total of 326 patients received vancomycin during the study period, of whom 200 met the inclusion criteria, representing 511 discrete episodes of prescribing by 42 pharmacists. The median overall competency rate, for all phases of prescribing, was 100% (interquartile range [IQR] 90.1%-100%). The median competency rates for the empiric therapy and monitoring phases were 94.4% (IQR 88.9%-100%) and 100% (IQR 87.5%-100%), respectively. No statistically significant differences were found in relation to pharmacists' experience or postbaccalaureate education, patients' level of acuity, or timing of prescribing. The competency score was significantly higher among pharmacists prescribing for patients with normal renal function than among those prescribing for patients with reduced renal function (p = 0.008). The 3 most common errors were failure to document risk factors for nephrotoxicity, failure to document requirement to obtain future trough levels, and failure to document that samples for trough levels had been drawn correctly.
CONCLUSIONS: During the study period, pharmacists at RQHR showed competency in all phases of vancomycin prescribing using the approved procedure. Documentation of clinical plans and assessments was identified as an area for improvement.

Entities:  

Keywords:  assessment; competency; compétence; pharmacien; pharmacist; vancomycin; vancomycine; évaluation

Year:  2017        PMID: 29109576      PMCID: PMC5659244          DOI: 10.4212/cjhp.v70i5.1694

Source DB:  PubMed          Journal:  Can J Hosp Pharm        ISSN: 0008-4123


  10 in total

1.  Vancomycin therapeutic guidelines: a summary of consensus recommendations from the infectious diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists.

Authors:  Michael J Rybak; Ben M Lomaestro; John C Rotschafer; Robert C Moellering; Willam A Craig; Marianne Billeter; Joseph R Dalovisio; Donald P Levine
Journal:  Clin Infect Dis       Date:  2009-08-01       Impact factor: 9.079

2.  Simple approach to dosage adjustment in patients with renal impairment.

Authors:  J P McCormack; J Cooper; B Carleton
Journal:  Am J Health Syst Pharm       Date:  1997-11-01       Impact factor: 2.637

3.  Evaluation of a Pharmacist-Directed Vancomycin Dosing and Monitoring Pilot Program at a Tertiary Academic Medical Center.

Authors:  Kathleen A Marquis; Jeremy R DeGrado; Stephanie Labonville; David W Kubiak; Paul M Szumita
Journal:  Ann Pharmacother       Date:  2015-05-19       Impact factor: 3.154

4.  Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children.

Authors:  Catherine Liu; Arnold Bayer; Sara E Cosgrove; Robert S Daum; Scott K Fridkin; Rachel J Gorwitz; Sheldon L Kaplan; Adolf W Karchmer; Donald P Levine; Barbara E Murray; Michael J Rybak; David A Talan; Henry F Chambers
Journal:  Clin Infect Dis       Date:  2011-01-04       Impact factor: 9.079

5.  Impact of pharmacist intervention on preventing nephrotoxicity from vancomycin.

Authors:  Nobutoshi Masuda; Takayoshi Maiguma; Atsushi Komoto; Yuto Haruki; Tetsuhiro Sugiyama; Sachiyo Kondo; Daisuke Teshima
Journal:  Int J Clin Pharmacol Ther       Date:  2015-04       Impact factor: 1.366

6.  Estimating creatinine clearance: a meta-analysis.

Authors:  Sheila M Wilhelm; Pramodini B Kale-Pradhan
Journal:  Pharmacotherapy       Date:  2011-07       Impact factor: 4.705

Review 7.  Systematic review and meta-analysis of vancomycin-induced nephrotoxicity associated with dosing schedules that maintain troughs between 15 and 20 milligrams per liter.

Authors:  S J van Hal; D L Paterson; T P Lodise
Journal:  Antimicrob Agents Chemother       Date:  2012-11-19       Impact factor: 5.191

Review 8.  Optimizing the Clinical Use of Vancomycin.

Authors:  Rocío Álvarez; Luis E López Cortés; José Molina; José M Cisneros; Jerónimo Pachón
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

9.  What proportion of vancomycin trough levels are drawn too early?: frequency and impact on clinical actions.

Authors:  Aileen P Morrison; Stacy E F Melanson; Marcy G Carty; David W Bates; Paul M Szumita; Milenko J Tanasijevic
Journal:  Am J Clin Pathol       Date:  2012-03       Impact factor: 2.493

Review 10.  Safety profiles of old and new antimicrobials for the treatment of MRSA infections.

Authors:  Matteo Bassetti; Elda Righi
Journal:  Expert Opin Drug Saf       Date:  2016-02-06       Impact factor: 4.250

  10 in total
  1 in total

1.  Experience of Vancomycin Therapeutic Drug Monitoring in Two Multidisciplinary Hospitals in Latvia.

Authors:  Inga Mauliņa; Karīna Darbiniece; Lāsma Miķelsone-Jansone; Renārs Erts; Dace Bandere; Angelika Krūmiņa
Journal:  Medicina (Kaunas)       Date:  2022-03-02       Impact factor: 2.430

  1 in total

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