Ipsita Sharma1, Deepa Venkatesh2, Geetanjali Bawa3, Syed Vaseemuddin4, Amit Joseph5, Jimmy K Sangtani6. 1. Department of Oral Pathology and Microbiology, RKDF Dental College and Research Center, Bhopal, Madhya Pradesh, India, Phone: +919713546173, e-mail: ipsita2326@gmail.com. 2. Department of Dentistry, Kodagu Institute of Medical Sciences Madikeri, Karnataka, India. 3. Private Practitioner, Amritsar, Punjab, India. 4. Department of Oral Medicine and Radiology, Dasmesh Institute of Research & Dental Sciences, Faridkot, Punjab, India. 5. Department of Oral Pathology and Microbiology, DAV Dental College, Solan, Himachal Pradesh, India. 6. Department of Orthodontics, Vidarbha Youth Welfare Society Amravati's Dental College & Hospital, Amravati, Maharashtra, India.
Abstract
INTRODUCTION: Odontogenic tumors (OTs) are a heterogeneous group of lesions that are derived from odontogenic apparatus comprised of odontogenic epithelium, ectomesenchyme, and/ or mesenchymal elements. The OTs show marked geographical variation. This study was conducted to analyze the epidemiology and clinicopathological presentation of OTs based on age, sex, and site. MATERIALS AND METHODS: This study was conducted in Department of Oral Pathology and Microbiology. Records were reviewed retrospectively for all the lesions of oral cavity from January 2010 to December 2015. A total of 92 lesions were found to be OTs and were classified into benign and malignant tumors. They were further subdivided into three subtypes based on the types of odontogenic tissues involved. These were epithelial OTs (EOTs), mixed OTs (MIXOTs), and mesenchymal OTs (MOTs). RESULTS: Of 92 OTs, 84 were benign (males 48, females 36) and 8 were malignant (male 2, females 6). The most common benign tumor was ameloblastoma (AME) (20), followed by keratocystic OT (KCOT) (17), calcifying EOT (CEOT) (14), compound odontome (OD-Cd) (12), complex odontome (OD-Cx) (10), odontogenic fibroma (OF) (5), odontogenic myxoma (OM) (4), and cementoblastoma (CB) (2). The most common malignant tumor was primary intraosseous squamous cell carcinoma (PIOSCC) (3) followed by fibrosarcoma (FS) (3) and ameloblastic carcinoma (AC). CONCLUSION: Author concluded that there was geographic and demographic variation in distribution of OTs, which may be attributed to socioeconomic and genetic factors. CLINICAL SIGNIFICANCE: Literature showing prevalence of OTs in India is negligible. By this article, we have analyzed the frequency of various OTs according to sex, age, and site. A comprehensive record of OTs should be started so that pathologists and surgeons would be able to acquire the information about the tumor for reference in the future.
INTRODUCTION:Odontogenic tumors (OTs) are a heterogeneous group of lesions that are derived from odontogenic apparatus comprised of odontogenic epithelium, ectomesenchyme, and/ or mesenchymal elements. The OTs show marked geographical variation. This study was conducted to analyze the epidemiology and clinicopathological presentation of OTs based on age, sex, and site. MATERIALS AND METHODS: This study was conducted in Department of Oral Pathology and Microbiology. Records were reviewed retrospectively for all the lesions of oral cavity from January 2010 to December 2015. A total of 92 lesions were found to be OTs and were classified into benign and malignant tumors. They were further subdivided into three subtypes based on the types of odontogenic tissues involved. These were epithelial OTs (EOTs), mixed OTs (MIXOTs), and mesenchymal OTs (MOTs). RESULTS: Of 92 OTs, 84 were benign (males 48, females 36) and 8 were malignant (male 2, females 6). The most common benign tumor was ameloblastoma (AME) (20), followed by keratocystic OT (KCOT) (17), calcifying EOT (CEOT) (14), compound odontome (OD-Cd) (12), complex odontome (OD-Cx) (10), odontogenic fibroma (OF) (5), odontogenic myxoma (OM) (4), and cementoblastoma (CB) (2). The most common malignant tumor was primary intraosseous squamous cell carcinoma (PIOSCC) (3) followed by fibrosarcoma (FS) (3) and ameloblastic carcinoma (AC). CONCLUSION: Author concluded that there was geographic and demographic variation in distribution of OTs, which may be attributed to socioeconomic and genetic factors. CLINICAL SIGNIFICANCE: Literature showing prevalence of OTs in India is negligible. By this article, we have analyzed the frequency of various OTs according to sex, age, and site. A comprehensive record of OTs should be started so that pathologists and surgeons would be able to acquire the information about the tumor for reference in the future.
Authors: Kleber Gruber; Silas Antonio Juvencio de Freitas Filho; Letícia Copatti Dogenski; Ana Carolina da Silva Bocassanta; Luiz Renato Paranhos; João Paulo de Carli Journal: Int J Surg Case Rep Date: 2019-04-05