Literature DB >> 29107568

ASK family in cardiovascular biology and medicine.

Tingting Liu1, Huanjiao Jenny Zhou2, Wang Min3.   

Abstract

Cardiovascular disease is a major cause of death worldwide. Mitogen-activated protein kinase (MAPK) signal cascades signaling pathways play crucial roles in cardiovascular pathophysiology. Apoptosis signal-regulating kinase (ASK) family members ASK1, ASK2 and ASK3 are the key molecules in MAPK signal cascades and are activated by various stresses. ASK1 is the most extensively studied MAPKKK and is involved in regulation of the cellular functions such as cell survival, proliferation, inflammation and apoptosis. The current review focuses on the relationship between ASK1 and cardiovascular disease, while exploring the novel therapeutic strategies for cardiovascular disease involved in the ASK1 signal pathway.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID： 29107568      PMCID： PMC5705453          DOI： 10.1016/j.jbior.2017.10.011

Source DB:  PubMed          Journal:  Adv Biol Regul        ISSN： 2212-4926


  85 in total

Review 1.  Transcriptional regulation by calcium, calcineurin, and NFAT.

Authors:  Patrick G Hogan; Lin Chen; Julie Nardone; Anjana Rao
Journal:  Genes Dev       Date:  2003-09-15       Impact factor: 11.361

2.  Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1.

Authors:  Kohsuke Takeda; Rieko Shimozono; Takuya Noguchi; Tsuyoshi Umeda; Yoshifumi Morimoto; Isao Naguro; Kei Tobiume; Masao Saitoh; Atsushi Matsuzawa; Hidenori Ichijo
Journal:  J Biol Chem       Date:  2007-01-08       Impact factor: 5.157

3.  Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress.

Authors:  K Morita; M Saitoh; K Tobiume; H Matsuura; S Enomoto; H Nishitoh; H Ichijo
Journal:  EMBO J       Date:  2001-11-01       Impact factor: 11.598

Review 4.  Pathophysiological roles of ASK1-MAP kinase signaling pathways.

Authors:  Hiroaki Nagai; Takuya Noguchi; Kohsuke Takeda; Hidenori Ichijo
Journal:  J Biochem Mol Biol       Date:  2007-01-31

Review 5.  NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease.

Authors:  Hua Cai
Journal:  Circ Res       Date:  2005-04-29       Impact factor: 17.367

Review 6.  ASK family and cancer.

Authors:  Hiroki Ryuno; Isao Naguro; Miki Kamiyama
Journal:  Adv Biol Regul       Date:  2017-05-20

Review 7.  Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling.

Authors:  Shigeru Shiizaki; Isao Naguro; Hidenori Ichijo
Journal:  Adv Biol Regul       Date:  2012-09-13

8.  AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation.

Authors:  Wang Min; Yan Lin; Shibo Tang; Luyang Yu; Haifeng Zhang; Ting Wan; Tricia Luhn; Haian Fu; Hong Chen
Journal:  Circ Res       Date:  2008-02-21       Impact factor: 17.367

9.  Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1.

Authors:  Go Fujino; Takuya Noguchi; Atsushi Matsuzawa; Shota Yamauchi; Masao Saitoh; Kohsuke Takeda; Hidenori Ichijo
Journal:  Mol Cell Biol       Date:  2007-08-27       Impact factor: 4.272

10.  Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling.

Authors:  Julian C Braz; Orlando F Bueno; Qiangrong Liang; Benjamin J Wilkins; Yan-Shan Dai; Stephanie Parsons; Joseph Braunwart; Betty J Glascock; Raisa Klevitsky; Thomas F Kimball; Timothy E Hewett; Jeffery D Molkentin
Journal:  J Clin Invest       Date:  2003-05       Impact factor: 14.808
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  5 in total

Review 1.  Mitochondrial abnormalities: a hub in metabolic syndrome-related cardiac dysfunction caused by oxidative stress.

Authors:  Aoxue Li; Ningning Zheng; Xudong Ding
Journal:  Heart Fail Rev       Date:  2021-05-05       Impact factor: 4.654

Review 2.  Psychological Stress and Cellular Aging in Cancer: A Meta-Analysis.

Authors:  Joanna Kruk; Basil Hassan Aboul-Enein; Joshua Bernstein; Magdalena Gronostaj
Journal:  Oxid Med Cell Longev       Date:  2019-11-13       Impact factor: 6.543

3.  DUSP12 acts as a novel endogenous protective signal against hepatic ischemia-reperfusion damage by inhibiting ASK1 pathway.

Authors:  Renzo Boldorini; Nausicaa Clemente; Elisa Alchera; Rita Carini
Journal:  Clin Sci (Lond)       Date:  2021-01-15       Impact factor: 6.124

4.  Ischemia/Reperfusion Injury of Fatty Liver Is Protected by A2AR and Exacerbated by A1R Stimulation through Opposite Effects on ASK1 Activation.

Authors:  Elisa Alchera; Bangalore R Chandrashekar; Nausicaa Clemente; Ester Borroni; Renzo Boldorini; Rita Carini
Journal:  Cells       Date:  2021-11-15       Impact factor: 6.600

Review 5.  Structural Insights Support Targeting ASK1 Kinase for Therapeutic Interventions.

Authors:  Veronika Obsilova; Karolina Honzejkova; Tomas Obsil
Journal:  Int J Mol Sci       Date:  2021-12-13       Impact factor: 5.923
  5 in total

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