Justin J Hourmozdi1, Jasreen Gill2, Joseph B Miller3, Abraham Markin3, Beth Adams4, Vivek Soi4, Anja K Jaehne2, Andrew R Taylor5, Sam Langberg6, Lauren Rodriguez2, Carynne Fox2, Junior Uduman7, Lenar T Yessayan8, Emanuel P Rivers9. 1. Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI. Electronic address: jhourmoz@icloud.com. 2. Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI. 3. Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI; Department of Internal Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI. 4. Division of Nephrology and Hypertension, Henry Ford Hospital, Wayne State University, Detroit, MI. 5. Public Health Sciences, Henry Ford Hospital, Wayne State University, Detroit, MI. 6. Department of Emergency Medicine, Detroit Receiving Hospital, Wayne State University, Detroit, MI. 7. Division of Nephrology and Hypertension, Henry Ford Hospital, Wayne State University, Detroit, MI; Division of Pulmonary and Critical Care Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI. 8. Department of Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI. 9. Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI; Department of Surgery, Henry Ford Hospital, Wayne State University, Detroit, MI.
Abstract
STUDY OBJECTIVE: Patients with end-stage renal disease commonly visit the emergency department (ED). The purpose of this investigation is to examine the prevalence of baseline abnormal lactate levels and to evaluate the effects of hemodialysis on serum lactate levels. METHODS: This was a prospective observational cohort study performed at an outpatient dialysis facility at an urban tertiary care hospital. The study consisted of 226 patients with end-stage renal disease who were receiving long-term hemodialysis and were enrolled during a 2-day period at the beginning of December 2015. Blood drawn for lactate levels was immediately analyzed before and after hemodialysis sessions. All patients completed their hemodialysis sessions. RESULTS: The prevalence of an abnormal lactate level (greater than 1.8 mmol/L) before hemodialysis was 17.7% (n=40). Overall, lactate levels decreased by 27% (SD 35%) after hemodialysis, with a decrease of 37% (SD 31%) for subgroups with a lactate level of 1.9 to 2.4 mmol/L, and 62% (SD 14%) with a lactate of 2.5 to 3.9 mmol/L. CONCLUSION: The data presented help providers understand the prevalence of abnormal lactate values in an outpatient end-stage renal disease population. After hemodialysis, lactate levels decreased significantly. This information may help medical providers interpret lactate values when patients with end-stage renal disease present to the ED.
STUDY OBJECTIVE:Patients with end-stage renal disease commonly visit the emergency department (ED). The purpose of this investigation is to examine the prevalence of baseline abnormal lactate levels and to evaluate the effects of hemodialysis on serum lactate levels. METHODS: This was a prospective observational cohort study performed at an outpatient dialysis facility at an urban tertiary care hospital. The study consisted of 226 patients with end-stage renal disease who were receiving long-term hemodialysis and were enrolled during a 2-day period at the beginning of December 2015. Blood drawn for lactate levels was immediately analyzed before and after hemodialysis sessions. All patients completed their hemodialysis sessions. RESULTS: The prevalence of an abnormal lactate level (greater than 1.8 mmol/L) before hemodialysis was 17.7% (n=40). Overall, lactate levels decreased by 27% (SD 35%) after hemodialysis, with a decrease of 37% (SD 31%) for subgroups with a lactate level of 1.9 to 2.4 mmol/L, and 62% (SD 14%) with a lactate of 2.5 to 3.9 mmol/L. CONCLUSION: The data presented help providers understand the prevalence of abnormal lactate values in an outpatientend-stage renal disease population. After hemodialysis, lactate levels decreased significantly. This information may help medical providers interpret lactate values when patients with end-stage renal disease present to the ED.
Authors: Chun Chieh Chu; Chih Min Su; Fu Cheng Chen; Chi Yung Cheng; Hsien Hung Cheng; Chia Te Kung Journal: Medicine (Baltimore) Date: 2021-02-19 Impact factor: 1.817
Authors: Ivana Stanimirova; Mirosław Banasik; Adam Ząbek; Tomasz Dawiskiba; Katarzyna Kościelska-Kasprzak; Wojciech Wojtowicz; Magdalena Krajewska; Dariusz Janczak; Piotr Młynarz Journal: Sci Rep Date: 2020-10-14 Impact factor: 4.379