| Literature DB >> 29106456 |
Jing Feng1, Yu Xiang2, Siyu Xia3, Huan Liu4, Jun Wang3, Fatma Muge Ozguc2, Lijun Lei3, Ruoshan Kong1, Lixia Diao5, Chunjiang He6, Leng Han2.
Abstract
Circular RNAs (circRNAs) are novel rising stars of noncoding RNAs, which are highly abundant and evolutionarily conserved across species. Number of publications related to circRNAs increased sharply in recent years, representing emerging focuses in the field. Therefore, tools, pipelines and databases have been developed to identify and store circRNAs. However, there is no existing tool to visualize and explore circRNAs. Therefore, we introduce CircView, a user-friendly visualization tool for circRNAs detected from existing tools. CircView enables users to visualize circRNAs and to quantify number of samples with detected circRNAs. CircView allows users to explore circRNAs detected by unique or multiple tools. Furthermore, CircView allows users to view the regulatory elements, such as microRNA response elements and RNA-binding protein binding sites. CircView is a unique tool to visualize and explore circRNAs, which helps users to better understand potential functions of circRNAs and design the functional experiments.Mesh:
Substances:
Year: 2018 PMID: 29106456 DOI: 10.1093/bib/bbx070
Source DB: PubMed Journal: Brief Bioinform ISSN: 1467-5463 Impact factor: 11.622