Literature DB >> 29105781

Prediction of mortality and morbidity in head and neck cancer patients 80 years of age and older undergoing surgery.

Heidi E L'Esperance1, Dorina Kallogjeri1, Shahnawaz Yousaf2, Jay F Piccirillo1, Jason T Rich1.   

Abstract

OBJECTIVES: To determine postoperative complications and mortality rates in octogenarian and older head and neck cancer patients undergoing ablative surgical resections and to identify factors associated with postoperative morbidity and mortality.
METHODS: Retrospective cohort study investigating risk factors for 30-day serious complication risk and 90-day mortality risk for patients aged 80 years and older who underwent ablative head and neck oncologic surgical procedures at an academic tertiary care center between 2005 and 2015.
RESULTS: Of the 219 patients who underwent 241 surgeries, 74 patients experienced serious complications within 30 days and 25 died within 90 days of surgery. American Society of Anesthesiologists (ASA) score of 4 or greater, and operating room (OR) time ≥6 hours were independently associated with serious complications, whereas age ≥90 years, overall severe comorbidity score, presence of preoperative dysphagia, and large extent of resection were associated with increased risk of death in 90 days. Models to predict risk of 30-day serious complications and 90-day mortality were then developed.
CONCLUSION: Patient and surgical treatment factors predict risk of serious complications and mortality in patients aged 80 years and older undergoing ablative head and neck surgery. Predictive models may guide preoperative discussion with patients. LEVEL OF EVIDENCE: 2b. Laryngoscope, 128:871-877, 2018.
© 2017 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  comorbidity; complications; elderly; frailty; head neck surgery; morbidity; mortality; octogenarian

Mesh:

Year:  2017        PMID: 29105781     DOI: 10.1002/lary.26858

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  6 in total

1.  Outcomes following head and neck cancer surgery among older adults as determined by an electronic geriatric assessment.

Authors:  Gabriel Raab; Daniel Restifo; Sean M McBride; Richard J Wong; Nancy Y Lee; Armin Shahrokni; Kaveh Zakeri
Journal:  J Geriatr Oncol       Date:  2021-10-28       Impact factor: 3.599

2.  Above and Beyond Age: Prediction of Major Postoperative Adverse Events in Head and Neck Surgery.

Authors:  Marco A Mascarella; Nikesh Muthukrishnan; Farhad Maleki; Marie-Jeanne Kergoat; Keith Richardson; Alex Mlynarek; Veronique-Isabelle Forest; Caroline Reinhold; Diego R Martin; Michael Hier; Nader Sadeghi; Reza Forghani
Journal:  Ann Otol Rhinol Laryngol       Date:  2021-08-20       Impact factor: 1.973

Review 3.  Management of Older Adults with Locally Advanced Head and Neck Cancer.

Authors:  Daniel R Dickstein; Eric J Lehrer; Kristin Hsieh; Alexandra Hotca; Brianna M Jones; Ann Powers; Sonam Sharma; Jerry Liu; Vishal Gupta; Loren Mell; Zain Husain; Diana Kirke; Krzysztof Misiukiewicz; Marshall Posner; Eric Genden; Richard L Bakst
Journal:  Cancers (Basel)       Date:  2022-06-05       Impact factor: 6.575

4.  Does age influence disease-specific survival in patients with squamous cell carcinomas of the head and neck?

Authors:  Joan Lop; Cristina Valero; Jacinto García; Miquel Quer; Ian Ganly; Jatin P Shah; Snehal G Patel; Xavier León
Journal:  J Surg Oncol       Date:  2020-03-09       Impact factor: 3.454

5.  Survival of Young Versus Old Patients With Oral Cavity Squamous Cell Carcinoma: A Meta-Analysis.

Authors:  David S Lee; Ricardo J Ramirez; Jake J Lee; Carla V Valenzuela; Jose P Zevallos; Angela L Mazul; Sidharth V Puram; Michelle M Doering; Patrik Pipkorn; Ryan S Jackson
Journal:  Laryngoscope       Date:  2020-12-02       Impact factor: 2.970

6.  Untreated head and neck cancer: Natural history and associated factors.

Authors:  Paul Zolkind; Jake J Lee; Ryan S Jackson; Patrik Pipkorn; Sean T Massa
Journal:  Head Neck       Date:  2020-09-11       Impact factor: 3.147

  6 in total

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