Literature DB >> 2910508

A new anticancer agent (LY186641) interferes with creatinine assay.

M M Bonnay1, G Recondo, A J Gouyette, J P Armand.   

Abstract

The administration of a diarylsulfonylurea, LY186641, which is presently undergoing a multicentric phase I clinical trial as an anticancer agent, produces major analytical interference with commonly used creatinine analysis techniques. We confirm that this interference is caused by a metabolite rather than the parent compound and propose an alternative, interference-free method.

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Year:  1989        PMID: 2910508     DOI: 10.1007/BF00273530

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN: 0344-5704            Impact factor:   3.333


  1 in total

1.  Mechanism of interference with the Jaffé reaction for creatinine.

Authors:  M H Kroll; N A Roach; B Poe; R J Elin
Journal:  Clin Chem       Date:  1987-07       Impact factor: 8.327

  1 in total

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