| Literature DB >> 29103009 |
Mohamed Faisal Abdul Hamid1, Andrea Ban Yu-Lin1, Tidi Maharani Hassan1, Nurashikin Mohammad2.
Abstract
A middle-aged woman with recurrent malignant melanoma presented initially with massive left pleural effusion. There was a complete obliteration of the left main bronchus on flexible bronchoscopy caused by a mass. Serial cryo-debulking of the tumour was done under rigid bronchoscopy; however, the outcome was not favourable due to the aggressive tumour growth. Vemurafenib was planned after thoracic radiation. She was not keen for the biologics treatment due to financial constraints. We report a case of central airway obstruction due to recurrent aggressive melanoma. More evaluations are needed on the role of interventional pulmonologist for bronchoscopic debulking of this rapidly growing tumour as well as the role of biological agents in treating such cases. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.Entities:
Keywords: dermatology; malignant disease and immunosuppression; respiratory cancer; respiratory system
Mesh:
Year: 2017 PMID: 29103009 PMCID: PMC5747808 DOI: 10.1136/bcr-2017-221545
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X