Literature DB >> 2910265

Etiology and mortality of status epilepticus in children. A recent update.

S A Phillips1, R J Shanahan.   

Abstract

We reviewed the medical records of 218 episodes of status epilepticus in 193 children who were admitted to the hospital between 1983 and 1987. Of the episodes, 61% were in boys and 39% in girls, with an age range of 1 month to 14 years (average, 3.2 years). The majority of episodes (73%) occurred in patients who were less than 5 years old, with 61% less than 3 years old and 28% less than 1 year old. Status epilepticus as the initial seizure occurred in 71% of episodes. In patients under 1 year of age, 75% of episodes were associated with acute causes (bacterial meningitis in 28% and electrolyte disorders in 30%), and 23% were idiopathic (19% associated with fever). In children less than 3 years old, 47% of episodes had an acute cause, 9% had a previously known seizure disorder, and 32% were idiopathic (30% associated with fever). In patients older than 3 years, 28% of episodes were associated with acute causes, 38% were known epileptics, and 13% were idiopathic (11% had fever). Overall mortality was 6%, with 1% of all episodes ending in death during the presenting seizure. We conclude that the etiology of status epilepticus is age related, with acute causes being more common in patients with a younger age at presentation. When our data are compared with other large studies in children, it appears that mortality associated with status epilepticus has decreased.

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Mesh:

Year:  1989        PMID: 2910265     DOI: 10.1001/archneur.1989.00520370076023

Source DB:  PubMed          Journal:  Arch Neurol        ISSN: 0003-9942


  12 in total

Review 1.  Treatment of status epilepticus in children.

Authors:  M De Negri; M G Baglietto
Journal:  Paediatr Drugs       Date:  2001       Impact factor: 3.022

Review 2.  Outcome of convulsive status epilepticus: a review.

Authors:  Claire L Novorol; Richard F M Chin; Rod C Scott
Journal:  Arch Dis Child       Date:  2007-11       Impact factor: 3.791

3.  Pinealectomy stimulates and exogenous melatonin inhibits harmful effects of epileptiform activity during pregnancy in the hippocampus of newborn rats: an immunohistochemical study.

Authors:  Mehmet Turgut; Yiğit Uyanikgil; Utku Ateş; Meral Baka; Mine E Yurtseven
Journal:  Childs Nerv Syst       Date:  2005-12-21       Impact factor: 1.475

Review 4.  Status epilepticus: pathophysiology, epidemiology, and outcomes.

Authors:  R C Scott; R A Surtees; B G Neville
Journal:  Arch Dis Child       Date:  1998-07       Impact factor: 3.791

Review 5.  Do seizures damage the brain? The epidemiological evidence.

Authors:  C M Verity
Journal:  Arch Dis Child       Date:  1998-01       Impact factor: 3.791

6.  Status epilepticus in Indian children in a tertiary care center.

Authors:  Sheffali Gulati; Veena Kalra; M R Sridhar
Journal:  Indian J Pediatr       Date:  2005-02       Impact factor: 1.967

7.  Outcome of childhood status epilepticus and lengthy febrile convulsions: findings of national cohort study.

Authors:  C M Verity; E M Ross; J Golding
Journal:  BMJ       Date:  1993-07-24

Review 8.  [Management of refractory status epilepticus from a neurologic and neuropediatric perspective].

Authors:  B Pohlmann-Eden; U Stephani; I Krägeloh-Mann; B Schmitt; U Brandl; M Holtkamp
Journal:  Nervenarzt       Date:  2007-08       Impact factor: 1.214

Review 9.  Fulminant hepatic failure associated with status epilepticus in children: three cases and a review of potential mechanisms.

Authors:  M K Decell; J B Gordon; K Silver; K Meagher-Villemure
Journal:  Intensive Care Med       Date:  1994-05       Impact factor: 17.440

10.  Factors associated with long-term outcomes in pediatric refractory status epilepticus.

Authors:  Marina Gaínza-Lein; Cristina Barcia Aguilar; Juan Piantino; Kevin E Chapman; Iván Sánchez Fernández; Marta Amengual-Gual; Anne Anderson; Brian Appavu; Ravindra Arya; James Nicholas Brenton; Jessica L Carpenter; Justice Clark; Raquel Farias-Moeller; William D Gaillard; Tracy A Glauser; Joshua L Goldstein; Howard P Goodkin; Linda Huh; Robert Kahoud; Kush Kapur; Yi-Chen Lai; Tiffani L McDonough; Mohamad A Mikati; Lindsey A Morgan; Anuranjita Nayak; Edward Novotny; Adam P Ostendorf; Eric T Payne; Katrina Peariso; Latania Reece; James Riviello; Kumar Sannagowdara; Tristan T Sands; Theodore Sheehan; Robert C Tasker; Dmitry Tchapyjnikov; Alejandra Vasquez; Mark S Wainwright; Angus Wilfong; Korwyn Williams; Bo Zhang; Tobias Loddenkemper
Journal:  Epilepsia       Date:  2021-07-12       Impact factor: 6.740

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