Literature DB >> 29102395

Nuclear inositide signaling and cell cycle.

Stefano Ratti1, Giulia Ramazzotti2, Irene Faenza2, Roberta Fiume2, Sara Mongiorgi2, Anna Maria Billi2, James A McCubrey3, Pann-Ghill Suh4, Lucia Manzoli2, Lucio Cocco2, Matilde Y Follo2.   

Abstract

Phosphatidylinositols (PIs) are responsible for several signaling pathways related to many cellular functions, such as cell cycle regulation at different check-points, cell proliferation, cell differentiation, membrane trafficking and gene expression. PI metabolism is not only present at the cytoplasmic level, but also at the nuclear one, where different signaling pathways affect essential nuclear mechanisms in eukaryotic cells. In this review we focus on nuclear inositide signaling in relation to cell cycle regulation. Many evidences underline the pivotal role of nuclear inositide signaling in cell cycle regulation and cell proliferation associated to different strategic physiopathological mechanisms in several cell systems and diseases.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Cell cycle; Differentiation; Disease; Nucleus; Phosphoinositides; Proliferation

Mesh：

Substances：

Year:  2017        PMID： 29102395     DOI： 10.1016/j.jbior.2017.10.008

Source DB:  PubMed          Journal:  Adv Biol Regul        ISSN： 2212-4926


  12 in total

1.  Phospholipase C delta 4 (PLCδ4) is a nuclear protein involved in cell proliferation and senescence in mesenchymal stromal stem cells.

Authors:  Marianna Kunrath-Lima; Marcelo Coutinho de Miranda; Andrea da Fonseca Ferreira; Camila Cristina Fraga Faraco; Mariane Izabella Abreu de Melo; Alfredo Miranda Goes; Michele Angela Rodrigues; Jerusa Araújo Quintão Arantes Faria; Dawidson Assis Gomes
Journal:  Cell Signal       Date:  2018-06-01       Impact factor: 4.315

Review 2.  CCAAT enhancer binding protein gamma (C/EBP-γ): An understudied transcription factor.

Authors:  Zachary Renfro; Bryan E White; Kimberly E Stephens
Journal:  Adv Biol Regul       Date:  2022-01-26

Review 3.  Nuclear phospholipase C isoenzyme imbalance leads to pathologies in brain, hematologic, neuromuscular, and fertility disorders.

Authors:  Stefano Ratti; Matilde Y Follo; Giulia Ramazzotti; Irene Faenza; Roberta Fiume; Pann-Ghill Suh; James A McCubrey; Lucia Manzoli; Lucio Cocco
Journal:  J Lipid Res       Date:  2018-10-04       Impact factor: 5.922

Review 4.  Diacylglycerol Kinase Alpha in Radiation-Induced Fibrosis: Potential as a Predictive Marker or Therapeutic Target.

Authors:  Chun-Shan Liu; Peter Schmezer; Odilia Popanda
Journal:  Front Oncol       Date:  2020-05-12       Impact factor: 6.244

5.  Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes.

Authors:  Matilde Y Follo; Andrea Pellagatti; Richard N Armstrong; Stefano Ratti; Sara Mongiorgi; Sara De Fanti; Maria Teresa Bochicchio; Domenico Russo; Marco Gobbi; Maurizio Miglino; Sarah Parisi; Giovanni Martinelli; Michele Cavo; Donata Luiselli; James A McCubrey; Pann-Ghill Suh; Lucia Manzoli; Jacqueline Boultwood; Carlo Finelli; Lucio Cocco
Journal:  Leukemia       Date:  2019-02-20       Impact factor: 11.528

Review 6.  Phosphoinositide 3 Kinase Signaling in Human Stem Cells from Reprogramming to Differentiation: A Tale in Cytoplasmic and Nuclear Compartments.

Authors:  Giulia Ramazzotti; Stefano Ratti; Roberta Fiume; Matilde Yung Follo; Anna Maria Billi; Isabella Rusciano; Eric Owusu Obeng; Lucia Manzoli; Lucio Cocco; Irene Faenza
Journal:  Int J Mol Sci       Date:  2019-04-24       Impact factor: 5.923

Review 7.  Phosphoinositide-Dependent Signaling in Cancer: A Focus on Phospholipase C Isozymes.

Authors:  Eric Owusu Obeng; Isabella Rusciano; Maria Vittoria Marvi; Antonietta Fazio; Stefano Ratti; Matilde Yung Follo; Jie Xian; Lucia Manzoli; Anna Maria Billi; Sara Mongiorgi; Giulia Ramazzotti; Lucio Cocco
Journal:  Int J Mol Sci       Date:  2020-04-08       Impact factor: 5.923

Review 8.  Subcellular Localization Relevance and Cancer-Associated Mechanisms of Diacylglycerol Kinases.

Authors:  Antonietta Fazio; Eric Owusu Obeng; Isabella Rusciano; Maria Vittoria Marvi; Matteo Zoli; Sara Mongiorgi; Giulia Ramazzotti; Matilde Yung Follo; James A McCubrey; Lucio Cocco; Lucia Manzoli; Stefano Ratti
Journal:  Int J Mol Sci       Date:  2020-07-26       Impact factor: 5.923

9.  HOXA5 is a tumor suppressor gene that is decreased in gastric cancer.

Authors:  Xudong Peng; Lang Zha; Anqi Chen; Ziwei Wang
Journal:  Oncol Rep       Date:  2018-07-02       Impact factor: 3.906

Review 10.  Nuclear Inositides and Inositide-Dependent Signaling Pathways in Myelodysplastic Syndromes.

Authors:  Jie Xian; Eric Owusu Obeng; Stefano Ratti; Isabella Rusciano; Maria Vittoria Marvi; Antonietta Fazio; Alessia De Stefano; Sara Mongiorgi; Alessandra Cappellini; Giulia Ramazzotti; Lucia Manzoli; Lucio Cocco; Matilde Yung Follo
Journal:  Cells       Date:  2020-03-12       Impact factor: 6.600
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