Literature DB >> 29100591

Outcomes of complicated appendicitis: Is conservative management as smooth as it seems?

Katelyn A Young1, Nina M Neuhaus2, Marcus Fluck3, Joseph A Blansfield4, Marie A Hunsinger5, Mohsen M Shabahang6, Denise M Torres7, Kenneth A Widom8, Jeffrey L Wild9.   

Abstract

BACKGROUND: This study characterized the failure rate of non-operative management (NOM) for complicated appendicitis (CA; perforation, abscess, phlegmon), and compared outcomes among patients undergoing acute appendectomy (AA), elective interval appendectomy (EIA), and unplanned appendectomy after failing to improve with NOM.
METHODS: Adults treated at one facility between 2007 and 2014 were retrospectively studied.
RESULTS: Ninety-five patients presented with CA. Sixty individuals underwent AA. The remaining 35 patients initially underwent NOM: 14 underwent EIA, nine (25.7%) failed NOM, 12 never underwent surgery. All patients failing NOM had an open operation with most (55.6%) requiring bowel resection. AA and EIA were comparable in surgical approach, bowel resection and post-operative readmission. However, AA demonstrated a lower incidence of bowel resection (3.3% vs 17.1%, P = 0.048) when compared to all patients initially undergoing NOM.
CONCLUSIONS: Due to the high incidence of failed NOM and the morbidity associated with failure, AA may be appropriate for CA.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Complicated appendicitis; Interval appendectomy; Perforated appendicitis

Mesh:

Year:  2017        PMID: 29100591     DOI: 10.1016/j.amjsurg.2017.10.032

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  16 in total

1.  Beware of the difference between randomized controlled trials and daily clinical practice (in reply to "Surgery or antibiotics for acute appendicitis? Take care about study's design and methodology!", by Ceresoli M, et al.).

Authors:  Mauro Podda; Gaetano Poillucci; Nicola Cillara
Journal:  Updates Surg       Date:  2018-05-18

2.  Comparison of conservative versus surgical therapy for acute appendicitis with abscess in five German hospitals.

Authors:  S Shekarriz; T Keck; P Kujath; J Shekarriz; T Strate; R Keller; E Schlöricke; J Nolde; A Ehlert; H Shekarriz
Journal:  Int J Colorectal Dis       Date:  2019-01-22       Impact factor: 2.571

3.  Diagnostic performance of standardized ultrasound protocol for detecting perforation in pediatric appendicitis.

Authors:  Erica L Riedesel; Blake C Weber; Matthew W Shore; Randi S Cartmill; Daniel J Ostlie; Charles M Leys; Kara G Gill; Jonathan E Kohler
Journal:  Pediatr Radiol       Date:  2019-07-24

4.  Laparoscopic Appendectomy Translates into Less Analgesics and Faster Return to Work in Asia.

Authors:  Anil Dinkar Rao; Chung Boon Daryl Tan; Reyaz Moiz Singaporewalla Md
Journal:  JSLS       Date:  2022 Apr-Jun       Impact factor: 1.789

5.  Perforated appendicitis in the setting of a massive ventral hernia, morbid obesity, and multiple severe comorbidities: challenges in acute management.

Authors:  Graham Skelhorne-Gross; David Gomez
Journal:  Trauma Surg Acute Care Open       Date:  2019-01-24

Review 6.  Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines.

Authors:  Salomone Di Saverio; Mauro Podda; Belinda De Simone; Marco Ceresoli; Goran Augustin; Alice Gori; Marja Boermeester; Massimo Sartelli; Federico Coccolini; Antonio Tarasconi; Nicola De' Angelis; Dieter G Weber; Matti Tolonen; Arianna Birindelli; Walter Biffl; Ernest E Moore; Michael Kelly; Kjetil Soreide; Jeffry Kashuk; Richard Ten Broek; Carlos Augusto Gomes; Michael Sugrue; Richard Justin Davies; Dimitrios Damaskos; Ari Leppäniemi; Andrew Kirkpatrick; Andrew B Peitzman; Gustavo P Fraga; Ronald V Maier; Raul Coimbra; Massimo Chiarugi; Gabriele Sganga; Adolfo Pisanu; Gian Luigi De' Angelis; Edward Tan; Harry Van Goor; Francesco Pata; Isidoro Di Carlo; Osvaldo Chiara; Andrey Litvin; Fabio C Campanile; Boris Sakakushev; Gia Tomadze; Zaza Demetrashvili; Rifat Latifi; Fakri Abu-Zidan; Oreste Romeo; Helmut Segovia-Lohse; Gianluca Baiocchi; David Costa; Sandro Rizoli; Zsolt J Balogh; Cino Bendinelli; Thomas Scalea; Rao Ivatury; George Velmahos; Roland Andersson; Yoram Kluger; Luca Ansaloni; Fausto Catena
Journal:  World J Emerg Surg       Date:  2020-04-15       Impact factor: 5.469

7.  The application of artificial intelligence methods to gene expression data for differentiation of uncomplicated and complicated appendicitis in children and adolescents - a proof of concept study.

Authors:  Josephine Reismann; Natalie Kiss; Marc Reismann
Journal:  BMC Pediatr       Date:  2021-06-08       Impact factor: 2.125

8.  Cost-effectiveness analysis of nonoperative management versus open and laparoscopic surgery for uncomplicated acute appendicitis in Colombia.

Authors:  César Augusto Guevara-Cuellar; María Paula Rengifo-Mosquera; Elizabeth Parody-Rúa
Journal:  Cost Eff Resour Alloc       Date:  2021-06-10

9.  Operative versus non-operative therapy for acute phlegmon of the appendix: Is it safer? A case report and review of the literature.

Authors:  Adel Elkbuli; Brandon Diaz; Valerie Polcz; Shaikh Hai; Mark McKenney; Dessy Boneva
Journal:  Int J Surg Case Rep       Date:  2018-08-01

10.  Outcomes of Open and Laparoscopic Appendectomy With Single Endoloop Stump Closure.

Authors:  Mitura Kryspin; Dorota Wyrzykowsk
Journal:  JSLS       Date:  2018 Oct-Dec       Impact factor: 2.172

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