Literature DB >> 2909903

Monozygotic twins concordant for the narcoleptic syndrome.

A B Douglass1, L Harris, F Pazderka.   

Abstract

We report the first documented monozygotic twins who both had the narcoleptic syndrome. We assessed monozygosity by HLA antigens and by blood groups. In contrast to virtually all other narcoleptics, they had HLA-DQ1 instead of HLA-DR2; this helped to localize the gene, and perhaps explains its greater expressivity in these than in other twins.

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Year:  1989        PMID: 2909903     DOI: 10.1212/wnl.39.1.140

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  4 in total

1.  The nature of apraxia in corticobasal degeneration.

Authors:  R Leiguarda; A J Lees; M Merello; S Starkstein; C D Marsden
Journal:  J Neurol Neurosurg Psychiatry       Date:  1994-04       Impact factor: 10.154

2.  The metabolic landscape of cortico-basal ganglionic degeneration: regional asymmetries studied with positron emission tomography.

Authors:  D Eidelberg; V Dhawan; J R Moeller; J J Sidtis; J Z Ginos; S C Strother; J Cederbaum; P Greene; S Fahn; J M Powers
Journal:  J Neurol Neurosurg Psychiatry       Date:  1991-10       Impact factor: 10.154

3.  Narcolepsy with cataplexy in monozygotic twins.

Authors:  Leonardo I Goulart; Mário Pedrazolli; Alexandre H Martori; Alan Eckeli; Heidi H Sander
Journal:  Sleep Sci       Date:  2014-09-10

4.  Treatment with immunosuppressive and anti-inflammatory agents delays onset of canine genetic narcolepsy and reduces symptom severity.

Authors:  L N Boehmer; M-F Wu; J John; J M Siegel
Journal:  Exp Neurol       Date:  2004-08       Impact factor: 5.330

  4 in total

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