| Literature DB >> 29098492 |
Esar Aysanoa1, Pedro Mayor2, A Patricia Mendoza3, Carlos M Zariquiey3, E Angelo Morales1, Jocelyn G Pérez3, Mark Bowler4, Julio A Ventocilla1, Carlos González5, G Christian Baldeviano1, Andrés G Lescano6,7.
Abstract
We determined the prevalence rate and risk of infection of Trypanosoma cruzi and other trypanosomatids in Peruvian non-human primates (NHPs) in the wild (n = 126) and in different captive conditions (n = 183). Blood samples were collected on filter paper, FTA cards, or EDTA tubes and tested using a nested PCR protocol targeting the 24Sα rRNA gene. Main risk factors associated with trypanosomatid and T. cruzi infection were genus and the human-animal context (wild vs captive animals). Wild NHPs had higher prevalence of both trypanosomatids (64.3 vs 27.9%, P < 0.001) and T. cruzi (8.7 vs 3.3%, P = 0.057), compared to captive NHPs, suggesting that parasite transmission in NHPs occurs more actively in the sylvatic cycle. In terms of primate family, Pitheciidae had the highest trypanosomatid prevalence (20/22, 90.9%) and Cebidae had the highest T. cruzi prevalence (15/117, 12.8%). T. cruzi and trypanosomatids are common in Peruvian NHPs and could pose a health risk to human and animals that has not been properly studied.Entities:
Keywords: Chagas; Epidemiology; Non-human primates; Prevalence; Trypanosoma cruzi; Trypanosomatids
Mesh：
Year: 2017 PMID： 29098492 PMCID： PMC5818207 DOI： 10.1007/s10393-017-1271-8
Source DB: PubMed Journal: Ecohealth ISSN： 1612-9202 Impact factor: 3.184