Chryssoula Tzialla1, Alberto Berardi2, Claudio Farina3, Pierangelo Clerici4, Alessandro Borghesi5, Elsa Viora6, Paolo Scollo7, Mauro Stronati5. 1. Neonatologia, Patologia Neonatale e Terapia Intensiva Neonatale, Fondazione IRCCS Policlinico, Viale Golgi 11, 27100, Pavia, Italy. c.tzialla@smatteo.pv.it. 2. Neonatal Intensive Care Unit, Policlinico University Hospital, Modena, Italy. 3. USC Microbiologia e Virologia ASST 'Papa Giovanni XXIII', Bergamo, Italy. 4. U.O. Microbiologia, A.S.S.T Ovest Milanese, Legnano, Italy. 5. Neonatologia, Patologia Neonatale e Terapia Intensiva Neonatale, Fondazione IRCCS Policlinico, Viale Golgi 11, 27100, Pavia, Italy. 6. SSD Ecografia Ostetrica-Ginecologica e Diagnosi Prenatale, Dipartimento di Ginecologia e Ostetricia, Azienda Ospedaliera Universitaria "Città della Salute e della Scienza", Torino, Italy. 7. Dipartimento Materno Infantile, UOC di Ostetricia e Ginecologia Azienda Ospedaliera Cannizzaro, Catania, Italy.
Abstract
BACKGROUND: There are no Italian data regarding the strategies for preventing neonatal group B streptococcal (GBS) infection. We conducted a national survey in order to explore obstetrical, neonatal and microbiological practices for the GBS prevention. METHODS: Three distinct questionnaires were sent to obstetricians, neonatologists and microbiologists. Questionnaires included data on prenatal GBS screening, maternal risk factors, intrapartum antibiotic prophylaxis, microbiological information concerning specimen processing and GBS antimicrobial susceptibility. RESULTS: All respondent obstetrical units used the culture-based screening approach to identify women who should receive intrapartum antibiotic prophylaxis, and more than half of the microbiological laboratories (58%) reported using specimen processing consistent with CDC guidelines. Most neonatal units (89 out of 107, 82%) reported using protocols for preventing GBS early-onset sepsis consistent with CDC guidelines. CONCLUSIONS: The screening-based strategy is largely prevalent in Italy, and most protocols for preventing GBS early-onset sepsis are consistent with CDC guidelines. However, we found discrepancies in practices among centers that may reflect the lack of Italian guidelines issued by public health organizations.
BACKGROUND: There are no Italian data regarding the strategies for preventing neonatal group B streptococcal (GBS) infection. We conducted a national survey in order to explore obstetrical, neonatal and microbiological practices for the GBS prevention. METHODS: Three distinct questionnaires were sent to obstetricians, neonatologists and microbiologists. Questionnaires included data on prenatal GBS screening, maternal risk factors, intrapartum antibiotic prophylaxis, microbiological information concerning specimen processing and GBS antimicrobial susceptibility. RESULTS: All respondent obstetrical units used the culture-based screening approach to identify women who should receive intrapartum antibiotic prophylaxis, and more than half of the microbiological laboratories (58%) reported using specimen processing consistent with CDC guidelines. Most neonatal units (89 out of 107, 82%) reported using protocols for preventing GBS early-onset sepsis consistent with CDC guidelines. CONCLUSIONS: The screening-based strategy is largely prevalent in Italy, and most protocols for preventing GBS early-onset sepsis are consistent with CDC guidelines. However, we found discrepancies in practices among centers that may reflect the lack of Italian guidelines issued by public health organizations.
Entities:
Keywords:
GBS; Group B streptococcus; Infection; Neonate; Newborn infant; Survey
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