Literature DB >> 2909658

Active and latent forms of transforming growth factor beta activity in synovial effusions.

R Fava1, N Olsen, J Keski-Oja, H Moses, T Pincus.   

Abstract

We have evaluated the possible involvement of TGF-beta in rheumatoid arthritis by assay of 16 cell-free synovial fluids for the presence of its active and "latent" forms. Evidence has been obtained for TGF-beta-like activity in synovial effusions by four criteria: (a) TGF-beta receptor competition, (b) soft-agar colony formation of AKR-2B and NRK-49F indicator cells, (c) immunological neutralization of the biological activity, and (d) biochemical activation of a latent form.

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Year:  1989        PMID： 2909658      PMCID： PMC2189180          DOI： 10.1084/jem.169.1.291

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  18 in total

1.  Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies.

Authors:  M Lotz; C D Tsoukas; C A Robinson; C A Dinarello; D A Carson; J H Vaughan
Journal:  J Clin Invest       Date:  1986-09       Impact factor: 14.808

2.  Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

Authors:  A B Roberts; M B Sporn; R K Assoian; J M Smith; N S Roche; L M Wakefield; U I Heine; L A Liotta; V Falanga; J H Kehrl
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

3.  Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

Authors:  R A Ignotz; J Massagué
Journal:  J Biol Chem       Date:  1986-03-25       Impact factor: 5.157

4.  Characterization of synovial fluid fibronectin from patients with rheumatic inflammatory diseases and healthy subjects.

Authors:  B Carnemolla; M Cutolo; P Castellani; E Balza; S Raffanti; L Zardi
Journal:  Arthritis Rheum       Date:  1984-08

5.  Serum contains a platelet-derived transforming growth factor.

Authors:  C B Childs; J A Proper; R F Tucker; H L Moses
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

6.  Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

Authors:  J H Kehrl; A B Roberts; L M Wakefield; S Jakowlew; M B Sporn; A S Fauci
Journal:  J Immunol       Date:  1986-12-15       Impact factor: 5.422

7.  Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

Authors:  S M Wahl; D A Hunt; H L Wong; S Dougherty; N McCartney-Francis; L M Wahl; L Ellingsworth; J A Schmidt; G Hall; A B Roberts
Journal:  J Immunol       Date:  1988-05-01       Impact factor: 5.422

8.  Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium.

Authors:  R M Lyons; J Keski-Oja; H L Moses
Journal:  J Cell Biol       Date:  1988-05       Impact factor: 10.539

9.  Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

Authors:  A E Postlethwaite; J Keski-Oja; H L Moses; A H Kang
Journal:  J Exp Med       Date:  1987-01-01       Impact factor: 14.307

10.  Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

Authors:  J H Kehrl; L M Wakefield; A B Roberts; S Jakowlew; M Alvarez-Mon; R Derynck; M B Sporn; A S Fauci
Journal:  J Exp Med       Date:  1986-05-01       Impact factor: 14.307
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  64 in total

Review 1.  The role of crystals in articular tissue degeneration.

Authors:  H S Cheung
Journal:  Curr Rheumatol Rep       Date:  1999-12       Impact factor: 4.592

Review 2.  The changing role of TGFβ in healthy, ageing and osteoarthritic joints.

Authors:  Peter M van der Kraan
Journal:  Nat Rev Rheumatol       Date:  2017-02-02       Impact factor: 20.543

3.  Platelets, but not erythrocytes, significantly affect cytokine release and scaffold contraction in a provisional scaffold model.

Authors:  May Jacobson; Duretti Fufa; Eduardo L Abreu; Sherwin Kevy; Martha M Murray
Journal:  Wound Repair Regen       Date:  2008 May-Jun       Impact factor: 3.617

Review 4.  The role of transforming growth factor-beta in inflammatory processes.

Authors:  S M Wahl
Journal:  Immunol Res       Date:  1991       Impact factor: 2.829

Review 5.  Cytokine therapy in rheumatoid arthritis.

Authors:  J Hermann; M Walmsley; F M Brennan
Journal:  Springer Semin Immunopathol       Date:  1998

6.  Hypoxia augments cytokine (transforming growth factor-beta (TGF-beta) and IL-1)-induced vascular endothelial growth factor secretion by human synovial fibroblasts.

Authors:  B Berse; J A Hunt; R J Diegel; P Morganelli; K Yeo; F Brown; R A Fava
Journal:  Clin Exp Immunol       Date:  1999-01       Impact factor: 4.330

7.  CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis.

Authors:  David Sancho; Manuel Gómez; Fernando Viedma; Enric Esplugues; Mónica Gordón-Alonso; María Angeles García-López; Hortensia de la Fuente; Carlos Martínez-A; Pilar Lauzurica; Francisco Sánchez-Madrid
Journal:  J Clin Invest       Date:  2003-09       Impact factor: 14.808

8.  Protection from interleukin 1 induced destruction of articular cartilage by transforming growth factor beta: studies in anatomically intact cartilage in vitro and in vivo.

Authors:  H M van Beuningen; P M van der Kraan; O J Arntz; W B van den Berg
Journal:  Ann Rheum Dis       Date:  1993-03       Impact factor: 19.103

9.  Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis.

Authors:  M Lotz; T Moats; P M Villiger
Journal:  J Clin Invest       Date:  1992-09       Impact factor: 14.808

10.  Thrombospondin-1 and transforming growth factor beta are pro-inflammatory molecules in rheumatoid arthritis.

Authors:  Mario C Rico; Joanne M Manns; Jeffrey B Driban; Audrey B Uknis; Satya P Kunapuli; Raul A Dela Cadena
Journal:  Transl Res       Date:  2008-07-11       Impact factor: 7.012
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