Jiayi Gu1, Jianqian Chao2, Wenji Chen3, Hui Xu4, Ruizhi Zhang5, Tingting He6, Lin Deng7. 1. Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China. Electronic address: 843899267@qq.com. 2. Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China. Electronic address: chaoseu@163.com. 3. Department of General Practice, Zhongda Hospital, Affiliated to Southeast University, Nanjing, Jiangsu, China. Electronic address: chwenji@163.com. 4. Hospital Office, Hospital of Qinhuai, Nanjing, Jiangsu, China. Electronic address: qhyyxh@yahoo.com. 5. Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China. Electronic address: 1814571929@qq.com. 6. Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China. Electronic address: 121147869@qq.com. 7. Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China. Electronic address: 1194898665@qq.com.
Abstract
OBJECTIVES: Multimorbidity is a growing public health problem. The objective of this study was to investigate the impact of multimorbidity on health-related quality of life (HRQoL) of the elderly. METHODS: A 24-month longitudinal study was conducted on the community-dwelling elderly. There were 411 elderly persons with complete follow-up. Information on thirteen chronic conditions was collected at baseline. Via a multi-dimensional scale, HRQoL was measured at baseline, 18 and 24 months post-baseline, respectively. Exploratory factor analyses were performed to identify multimorbidity patterns. The linear mixed effects models were conducted to analyze the associations between all dimensions of HRQoL and multimorbidity including distinct multimorbidity patterns. RESULTS: Multimorbidity was found to be negatively associated with HRQoL except memory function. We identified three multimorbidity patterns, which were mainly labelled as degenerative disorders, digestive/respiratory disorders, cardiovascular/metabolic disorders, respectively. And three multimorbidity patterns were associated with lower HRQoL including general health, body function, self-care ability and social adaptability. Besides, the elderly with the multimorbidity pattern mainly labelled as digestive/respiratory disorders or cardiovascular/metabolic disorders had a decline on emotion than those without multimorbidity. According to the analysis of the longitudinal data of the sample, general health, self-care ability, emotion and social adaptability of the participants decreased in different degrees every month. CONCLUSIONS: Multimorbidity was associated with lower HRQoL of the community-dwelling elderly. Distinct multimorbidity patterns had various impacts on different dimensions of HRQoL. Further studies should be carried out to investigate effective measures to improve HRQoL of the elderly with multimorbidity.
OBJECTIVES: Multimorbidity is a growing public health problem. The objective of this study was to investigate the impact of multimorbidity on health-related quality of life (HRQoL) of the elderly. METHODS: A 24-month longitudinal study was conducted on the community-dwelling elderly. There were 411 elderly persons with complete follow-up. Information on thirteen chronic conditions was collected at baseline. Via a multi-dimensional scale, HRQoL was measured at baseline, 18 and 24 months post-baseline, respectively. Exploratory factor analyses were performed to identify multimorbidity patterns. The linear mixed effects models were conducted to analyze the associations between all dimensions of HRQoL and multimorbidity including distinct multimorbidity patterns. RESULTS: Multimorbidity was found to be negatively associated with HRQoL except memory function. We identified three multimorbidity patterns, which were mainly labelled as degenerative disorders, digestive/respiratory disorders, cardiovascular/metabolic disorders, respectively. And three multimorbidity patterns were associated with lower HRQoL including general health, body function, self-care ability and social adaptability. Besides, the elderly with the multimorbidity pattern mainly labelled as digestive/respiratory disorders or cardiovascular/metabolic disorders had a decline on emotion than those without multimorbidity. According to the analysis of the longitudinal data of the sample, general health, self-care ability, emotion and social adaptability of the participants decreased in different degrees every month. CONCLUSIONS: Multimorbidity was associated with lower HRQoL of the community-dwelling elderly. Distinct multimorbidity patterns had various impacts on different dimensions of HRQoL. Further studies should be carried out to investigate effective measures to improve HRQoL of the elderly with multimorbidity.
Authors: Catarina Covolo Scarabottolo; Edilson Serpeloni Cyrino; Priscila Missaki Nakamura; William Rodrigues Tebar; Daniel da Silva Canhin; Luis Alberto Gobbo; Diego Giulliano Destro Christofaro Journal: BMJ Open Date: 2019-06-27 Impact factor: 2.692
Authors: Maylos Rodrigo-Claverol; Carles Casanova-Gonzalvo; Belén Malla-Clua; Esther Rodrigo-Claverol; Júlia Jové-Naval; Marta Ortega-Bravo Journal: Int J Environ Res Public Health Date: 2019-08-09 Impact factor: 3.390
Authors: Dexing Zhang; Regina Wing Shan Sit; Carmen Wong; Dan Zou; Stewart W Mercer; Marjorie C Johnston; Samuel Yeung Shan Wong Journal: BMJ Open Date: 2020-02-20 Impact factor: 2.692
Authors: Ruth E Pel-Littel; Cynthia S Hofman; Liesje Yu; Silke F Metzelthin; Franca H Leeuwis; Jeanet W Blom; B M Buurman; Mirella M Minkman Journal: PLoS One Date: 2019-11-20 Impact factor: 3.240