I C Zibrandtsen1, P Kidmose2, C B Christensen2, T W Kjaer3. 1. Neurophysiological Center, Neurological Department, Zealand University Hospital, Roskilde, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark. Electronic address: icz@regionsjaelland.dk. 2. Department of Engineering, Aarhus University, Aarhus, Denmark. 3. Neurophysiological Center, Neurological Department, Zealand University Hospital, Roskilde, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark.
Abstract
OBJECTIVE: Ear-EEG is recording of electroencephalography from a small device in the ear. This is the first study to compare ictal and interictal abnormalities recorded with ear-EEG and simultaneous scalp-EEG in an epilepsy monitoring unit. METHODS: We recorded and compared simultaneous ear-EEG and scalp-EEG from 15 patients with suspected temporal lobe epilepsy. EEGs were compared visually by independent neurophysiologists. Correlation and time-frequency analysis was used to quantify the similarity between ear and scalp electrodes. Spike-averages were used to assess similarity of interictal spikes. RESULTS: There were no differences in sensitivity or specificity for seizure detection. Mean correlation coefficient between ear-EEG and nearest scalp electrode was above 0.6 with a statistically significant decreasing trend with increasing distance away from the ear. Ictal morphology and frequency dynamics can be observed from visual inspection and time-frequency analysis. Spike averages derived from ear-EEG electrodes yield a recognizable spike appearance. CONCLUSIONS: Our results suggest that ear-EEG can reliably detect electroencephalographic patterns associated with focal temporal lobe seizures. Interictal spike morphology from sufficiently large temporal spike sources can be sampled using ear-EEG. SIGNIFICANCE: Ear-EEG is likely to become an important tool in clinical epilepsy monitoring and diagnosis.
OBJECTIVE: Ear-EEG is recording of electroencephalography from a small device in the ear. This is the first study to compare ictal and interictal abnormalities recorded with ear-EEG and simultaneous scalp-EEG in an epilepsy monitoring unit. METHODS: We recorded and compared simultaneous ear-EEG and scalp-EEG from 15 patients with suspected temporal lobe epilepsy. EEGs were compared visually by independent neurophysiologists. Correlation and time-frequency analysis was used to quantify the similarity between ear and scalp electrodes. Spike-averages were used to assess similarity of interictal spikes. RESULTS: There were no differences in sensitivity or specificity for seizure detection. Mean correlation coefficient between ear-EEG and nearest scalp electrode was above 0.6 with a statistically significant decreasing trend with increasing distance away from the ear. Ictal morphology and frequency dynamics can be observed from visual inspection and time-frequency analysis. Spike averages derived from ear-EEG electrodes yield a recognizable spike appearance. CONCLUSIONS: Our results suggest that ear-EEG can reliably detect electroencephalographic patterns associated with focal temporal lobe seizures. Interictal spike morphology from sufficiently large temporal spike sources can be sampled using ear-EEG. SIGNIFICANCE: Ear-EEG is likely to become an important tool in clinical epilepsy monitoring and diagnosis.
Authors: A Schulze-Bonhage; S Böttcher; M Glasstetter; N Epitashvili; E Bruno; M Richardson; K V Laerhoven; M Dümpelmann Journal: Nervenarzt Date: 2019-12 Impact factor: 1.214
Authors: Amirhossein Jahanbekam; Jan Baumann; Robert D Nass; Christian Bauckhage; Holger Hill; Christian E Elger; Rainer Surges Journal: Epilepsia Open Date: 2021-07-20